Tau [pS199] and Tau [pS214] phosphospecific antibodies (Cat.no.44-742); CV-1 cells transfected with full length adult human Tau and treated with okadaic acid to inhibit endogenous PP2A were incubated with Tau [pS199] (left) or Tau [pS214] (right). Data show that differential phosphorylation of Tau can influence the subcellular/cytoskeletal localization of Tau, including whether it remains bound to microtubules or is found soluble in the cytoplasm.