ST-486 Burkitt’s lymphoma cells cultured in SensiCell™ media with 10% FBS display an increased apoptotic response to TRAIL ligand and greater assay signal-to-noise ratio compared to cells cultured in standard media.
ST-486 cells were treated with different concentrations of TRAIL ligand for 40 hours followed by assessment of viable cells using a bioluminescent cell viability reagent. Cells maintained in SensiCell™ media show both an increased sensitivity to ligand as well as an improvement in overall signal-to-noise ratio of the assay.
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