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Cell Lines Detail

Cell Line Name:

LoVo

Organism Type:

Human

Tissues:

Colon

Adherence Phenotype:

Adherent

Primary:

No

Scientific Application(s):

Transient Transfection

Comments:

These cells are epithelial cells. LoVo was isolated in 1971 from a fragment of a metastatic tumor nodule in the left supraclavicular region of a 56-year-old Caucasian male patient with a histologically proven diagnosis of adenocarcinoma of the colon. The cells are negative for expression of CSAp (CSAp-) and colon antigen 3. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. Myb, and fos oncogenes. N-myc and sis oncogene expression were not detected. Tumor specific nuclear matrix proteins CC-3 and CC-4 are expressed (ATTC).

 

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