Technical Resources - Cell Line Database

Cell Lines Detail

Cell Line Name:

CHO-Lec2

Organism Type:

Hamster

Tissues:

Ovary

Adherence Phenotype:

Adherent

Primary:

No

Scientific Application(s):

Transient Transfection

Comments:

CHO-Lec2 cells are mutants that have a 70–90% de- ficiency of sialic acid in their glycoproteins and gangliosides. Transport of CMP-sialic acid into the Golgi vesicles of these cells was 90% defective compared to vesicles from wild-type cells, whereas transport of other nucleotide sugars was normal. These cells do not have a defect in biosynthesis of CMP-sialic acid, asialoglycoproteins, and asialoglycosphingolipids, and they have normal levels of sialyltransferases.

 

Products and applications for " CHO-Lec2 "
Media/Cell Culture 1
Transfection Display 3
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