In order to assist laboratories in standardizing to units set by the World Health Organization (WHO) for Epstein-Barr virus (EBV) nucleic acid testing, we now provide traceability to the 1st WHO International Standard for EBV with AcroMetrix® EBV panels and controls.

A conversion factor between AcroMetrix® EBV copies (cp) and International Units (IU) has been established as:

10 AcroMetrix® EBV copies = 1 EBV International Unit

Currently, certificates of analysis will display both copies and IU, but eventually we will label EBV Panels only in IU/mL. Viral concentrations in each control or panel member have not changed, so your results with AcroMetrix® controls and panels should remain consistent.

Please see the tables below for target values in IU/mL for our EBV panels.

AcroMetrix® EBV CSF Panel (Cat. No. 942015)

Panel member

Target value (copies)

Target value (IU)

Fill Vol.

0

Negative

Negative

0.5 mL

1E3

1,000 cp/mL

100 IU/mL

0.5 mL

1E4

10,000 cp/mL

1,000 IU/mL

0.5 mL

1E5

100,000 cp/mL

10,000 IU/mL

0.5 mL

1E6

1,000,000 cp/mL

100,000 IU/mL

0.5 mL



AcroMetrix® EBV Plasma Panel (Cat. No. 942017A)

Panel member

Target value (copies)

Target value (IU)

Fill Vol.

1E3

1,000 cp/mL

100 IU/mL

0.5 mL

1E4

10,000 cp/mL

1,000 IU/mL

0.5 mL

1E5

100,000 cp/mL

10,000 IU/mL

0.5 mL

1E6

1,000,000 cp/mL

100,000 IU/mL

0.5 mL

1E7

10,000,000 cp/mL

1,000,000 IU/mL

0.5 mL


Find AcroMetrix® EBV CSF Panel Certificate of Analysis

Find AcroMetrix® EBV Plasma Panel Certificate of Analysis