Cancer Epigenetics
 | The initiation and progression of cancer, traditionally seen as a genetic disease, is now realized to involve epigenetic abnormalities along with genetic alterations. Recent advancements in the rapidly evolving field of cancer epigenetics have shown that disruption of various epigenetic mechanisms includes non-coding RNAs, such as microRNAs, DNA methylation, histone modifications, and nucleosome positioning are central to switching normal cells to malignant cells. Life Technologies has developed powerful epigenetic research technologies spanning renewable antibody development, sample preparation, sequencing, quantitative PCR, & functional analysis assays to help unlock the mysteries of the cancer cell. |
Noncoding RNA
Discover the noncoding RNAs that regulate cancer RNA Sequencing
MicroRNA & Small RNA Isolation MicroRNA Profiling & Validation Functional Analysis (in vitro or in vivo) |
Chromatin Analysis
Read, write, & erase the epigenetic code through dynamic protein-DNA complexes Map Proteins Across the Genome Understand Chromatin Structure Investigate Enzymes & Substrate Modifications Profile Chromatin Enzymes or Substrates |
DNA Methylation
Analyze DNA methylation because not all genes are active all the time
Fractionate CpG Methylation Density |
Renewable Epigenetic Antibodies
Epigenetic regulatory proteins are involved in a wide variety of chronic diseases, such as cancer, and are the target of an explosive new field of drug discovery. The ability to properly study most epigenetic changes, which determine which genes are “turned off and on,” are determined by the effectiveness of one critical tool—antibodies. Life Technologies has partnered with the Structural Genomics Consortium (SGC) to develop high-quality recombinant antibodies to read, write, and erase the epigenetic code.
All products referenced are for Research Uses Only and are not intended for human or animal therapeutic or diagnostic uses.
