Stem Cell Reprogramming Tools

Generation of induced pluripotent stem cells (iPSCs) requires efficient delivery of reprogramming factors into somatic cells.

Lentivirus transduction is the most commonly used method of somatic cell reprogramming, due in large part to the potency of lentiviral vectors for transduction of both dividing and non-dividing cells. For flexible reprogramming of fibroblasts, customize your iPSC experiments by choosing from eight different high-titer lentiviral constructs.

For higher performance, particularly when reprogramming challenging cell types such as CD34+ cells or Peripheral blood mononuclear cells (PBMCs), we recommend the CytoTune™ -iPS Sendai Virus Reprogramming Kit: a highly efficient, easy-to-use non-integrating Sendai virus technology for generating induced pluripotent stem cells.

Which stem cell reprogramming tool is right for you?

  Standard Performance
Product description Well-referenced, flexible technology for iPSC generation from multiple somatic cell types Efficient generation of integration-free iPSCs especially from challenging cell types including blood
Reprogramming efficiency 0.001-0.01% 0.01-1%
Genomic integration-free No Yes
Hands-on time One application One application
Blood cell reprogramming No Yes
Convenience hOct4-GFP and CMV-GFP reporters available for transduction and expression verification Kit contains all 4 genes required
Cannot be purchased separately
Price $300 per particle $1995 per kit
Available support resources yesyes
Standard protocol for fibroblast reprogramming
yesyesyesyes
Protocols for fibroblast,
CD34+, PBMC reprogramming.
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