Ion PGM™ Sequencer

The Fastest Benchtop Sequencing Solution

Powered by Ion Torrent™ semiconductor chip technology, the Ion Personal Genome Machine™ (PGM™) Sequencer delivers the fastest run times, at the most affordable price, of any next-generation sequencer. High accuracy, and long reads put the Ion PGM™ Sequencer in a class of its own and makes next-generation sequencing more accessible to scientists around the world.

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Dr. Niall J. Lennon, is the Assistant Director of Process Development Genome Sequencing at the Broad Institute of MIT and Harvard. Dr. Lennon discusses how the Broad is using the Ion Torrent PGM.

At the 2012 AGBT conference Dr. Tim Triche gives a great talk on long-read RNA-Seq, splice isoforms and novel RNA transcript detection on the Ion PGM sequencer.

Product Announcements

Ion AmpliSeq™ Target Selection Technology

Ready-to-use and Custom Panels transform your research with just 10 ng of DNA. Simple, fast, and affordable targeted sequencing for hundreds of genes using challenging samples (FFPE).

Transform your research today

Paired-end Sequencing

Ion paired-end sequencing (PES) protocols for sequencing of 2 x 100 base reads nearly doubles the sequence output per chip and increases accuracy across the read. PES is ideal for improving de novo assembly, increasing the accuracy of sequencing, and identifying genomic and transcriptional variation. The PES protocol will be extended in Q2 2012 with the release of a 2 x 200 base paired-end sequencing kit.

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Ion PGM™ Sequencer Workflow

1 Construct Library

Ion Torrent library kits offer novel fragmentation processes that reduce library prep time.

2 Prepare Template

The Ion OneTouch™ System for template preparation is fully automated and requires just minutes of hands-on time

3 Run Sequence

The Ion PGM™ Sequencer is ideal for sequencing small genomes, sets of genes, or performing gene expression profiling or ChIP-Seq. Using Ion AmpliSeq™ Custom Solutions, researchers can interrogate targeted genomic regions using up to 1,536 amplicons in a single tube, in a single day.

4 Analyze Data

Torrent Suite analysis software delivers significant improvement in base-call accuracy while cutting analysis time to a minimum.