DNA Sequencing With the 5500xl Genetic Analyzer
The introduction of massively parallel, next-generation sequencing has dramatically expanded the range of possibilities in DNA analysis. The 5500xl Genetic Analyzer gives you the throughput, accuracy, and flexibility to tackle them all.
DNA Sequencing Research Applications
DNA sequencing research applications can be broadly divided into two groups, de novo sequencing (no reference genome is required) and a variety of resequencing applications (compares the results of the sequencing experiment to an available reference genome).
Select your area of interest:
Sequence is compared to a reference genome to detect the full range of genetic variation such as SNPs, insertions, deletions, inversions, complex rearrangements, and copy number variation. Resequencing can involve the whole genome or a selected portion of it:
When no reference is available, de novo sequencing and assembly allows the production of a draft or even finished genome