Genome & DNA Sequence Analysis
 For discovering novel traits, better understanding disorders, or applying genetic information to solve real-world problems, Life Technologies delivers DNA sequencing systems and complete research workflows to unlock the genome, offering you the accuracy and high performance systems you need to help answer biology’s most challenging questions. The Life Technologies portfolio supports a wide range of throughput and research application needs for DNA sequencing and fragment analysis. Whether it’s the Applied Biosystems® Genetic Analyzers for next-generation and Sanger sequencing or the Ion Torrent™ Personal Genome Machine™ sequencer for benchtop sequencing, you can find the research application solution on the platform that is right for you. Which platform is right for you? Choose from DNA sequencing research applications, which can be broadly divided into two groups: de novo sequencing (where no reference genome is required) and re-sequencing applications (sequence data is compared to a reference genome). Also, select proven fragment analysis products for Applied Biosystems® Genetic Analyzers to explore different applications such as SNP analysis, linkage studies, human identification, copy number, and more. |
DNA Sequencing: | Fragment Analysis: | |||
 | Resequencing Applications Sequence is compared to a reference genome to detect the full range of genetic variation such as SNPs, insertions, deletions, inversions, complex rearrangements, and copy number variation. Resequencing can involve the whole genome or a selected portion of it. |  | Microsatellite-based Applications Using Capillary Electrophoresis The vast amount of data emerging for thousands of microsatellite markers across organisms makes microsatellite analysis a widely accepted tool for linkage and association studies, and also for identifying individual organisms (i.e., human identification or HID). | |
 | De Novo Sequencing When no reference is available, de novo sequencing and assembly allows the production of a draft or even finished genome. |  | Relative Fluorescent Quantification Using Capillary Electrophoresis Relative fluorescent quantitation (or quantitative fluorescence PCR (QF-PCR) is a technique used in a variety of fragment analysis applications that requires accurate peak height comparisons across multiple samples. | |
 | Validation & Library Assessment Using Semiconductor Sequencing Validation of whole genome and whole exome mutation. |  | AFLP, RFLP, SSCP & BAC Fragment Analysis Fragment analysis is used for genotyping and detecting genetic variation. With a large selection of reagents and workflows for a wide variety of research applications, we can help you find the fragment analysis application that fits for your needs. | |
 | SNP Analysis SNP genotyping identifies single nucleotide polymorphisms (SNPs) that are common DNA variants present across the human genome. | |||
