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in vivo RNAi

A solution for successful in vivo RNAi
In vivo RNAi experiments are more challenging than their in vitro counterparts due to the demands of the cellular environment. These added challenges necessitate the use of the highest-quality materials to obtain meaningful results. Invitrogen offers a complete solution for successful in vivo RNAi experiments including the highest quality chemically modified siRNA.

Stealth RNAi™ siRNA - in vivo-ready duplexes

Chemically modified RNAi duplexes for specificity, stability, and effective knockdown

Stealth RNAi™ siRNA overcomes many  in vivo-specific obstacles, ensuring effectiveness and stability in in vivo applications. Learn why Stealth RNAi™ siRNA is the gold standard:

  • High stability against nucleases
  • No induction of the interferon response
  • Easy tracking of administered RNAi duplexes
  • Knockdown effectiveness and stability
  • Award-winning design algorithm
Ambion® Silencer® and Silencer® Select siRNAs are also available in “in vivo format”—with the extra level of purification and testing required for introduction into animals. When ordering your next Silencer® or Silencer® Select siRNA, simply choose "In Vivo" when selecting the siRNA purity level.  

in vivo RNAi Research Considerations