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Protein Sample Preparation & Protein Purification

Protein Purification Advance your proteomic workflows using Invitrogen’s comprehensive portfolio of products.  You can simplify protein sample preparation and reduce protein sample complexity prior to mass spectrometry.  You can isolate peptides, proteins, protein complexes and even sub-cellular compartments directly from your crude sample for further analysis. We offer attractive and reliable solutions to academic and industrial researchers, diagnostic companies and biotech OEMs.

Immunoprecipitation

For small scale, reproducible protein pull downs, magnetic beads coated with protein A or G is a fast and automatable solution. Protein A  or G agarose is provided for bulk purifications.



Protein Complex Pull-Downs

’In solution’ magnetic bead protein pull-down is both gentle and fast. This allowing for large protein complexes to be isolated intact without  breaking the weak ion-bonds between interacting proteins.

Learn more about His-Tagged Protein Isolation & Pulldown using Dynabeads®


Protein Sample Fractionation

Reduce the complexity of your sample. Smaller fractions can be achieved by exploiting differences in protein charge or hydrophobicity using magnetic bead chromatography. Serum samples can easily be fractionated for peptide profiling using Dynabeads®. Complexity can also be reduced by organelle isolation. Separation can be done based on isoelectric point of proteins using the ZOOM® IEF Fractionator.


Protein & Peptide Purification

'In solution' magnetic separation technology makes purifying proteins, peptides and even large protein complexes easy, fast and gentle. For your specific application, choose from a wide range of Dynabeads® and other protein purification reagents.


Chromatography

We offer a broad range of chromatography reagents for protein and antibody purification, including products for affinity chromatography, anion exchange chromatography, and other applications.

Organelle Isolation

Sample complexity reduction prior to analysis can be achieved by organelle isolation with magnetic separation technology.


Cell Lysis

Use cell lysis reagents and kits to access your proteins of interest derived from whole cells.