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ProtoArray® users meeting

Geneva, Switzerland, Sept 9th 2009

Protein Expression & Analysis

Biomarker Discovery with ProtoArray®


 Discover Biomarkers with ProtoArray® Protein Microarrays
Discover novel autoantibody markers for cancer and autoimmune diseases. Only ProtoArray® technology enables:

  • Results in less than one day
  • Use of as little as 10 µl of sera or plasma
  • A simple protocol to profile over 9,000 proteins

View new biomarker discovery resources and ordering information.

ProtoArray®

  • ProtoArray®  New Version 5.0 released
  • ProtoArray®  Prospector Version 5.2 released

Current Research & News

  • ProtoArray® Human Protein Microarray—Better Than Ever!
    New Version 5.0 released!


    Controls include:
    • Positional mapping agent for radiolabeled small molecule profiling
    • Positive controls for ubiquitination and sumoylation studies
    • Control content for optimized data normalization algorithm for biomarker discovery
    • Human IgA and anti-human IgA gradients to allow for IgA serum antibody profiling

    New ProtoArray® Prospector v5.2 software include:
    • Optimized report output and data normalization
    • New algorithms for analysis of small molecule profiling data
    • Auto-update feature

    ProtoArray® protein arrays created “atlas” for transplant rejection

    Chronic injury in renal transplantation had been examined using over 5,000 proteins on the ProtoArray® protein array. All of the auto antibodies present post transplantation were profiled. Specific non-HLA targets were identified in the auto antibodies generated post transplant. These targets were profiled using the ProtoArray® array and a genetic database. The resulting auto antibodies were mapped to specific renal targets. The non-HLA targets did not exist in other organs.

    Learn more about ProtoArray® protein arrays and transplant rejection.  

Capabilities & Tools

  • ProtoArray® Prospector v5.2
    A freeware tool for the analysis of data from protein-protein interaction and kinase substrate identification, and immune response biomarker profiling experiments.

    Building the human proteome
    Find out if your protein of interest is on the human ProtoArray® microarray.