Drug Metabolism Enzyme (DME) Genotyping with Real-Time PCR

TaqMan® Drug Metabolism Genotyping Assays offer the broadest menu of drug metabolism enzyme (DME) targets on the market, offering 2,700 unique assays that detect polymorphisms in 221 genes for high-value DMEs and associated transporter targets. The products use 5´ nuclease assay chemistry for amplifying and detecting specific SNP alleles, multinucleotide polymorphisms (MNPs) and insertion/deletions (InDels).

  • Helps accurately detect biologically important polymorphisms with roles in drug metabolism and transport
  • Available as individual ready-to-use tubes or custom plating
  • 95% covarage of ADME core markers defined by the PharmaADME consortium
  • Work confidently—our bioinformatics mapping, design, and in silico QC means you are studying the right SNP
  • Get started immediately with ready-to-use assays optimized for all Applied Biosystems® real-time PCR systems

Experimental Workflow: Find the Products You Need for Every Step

Isolate and purify genomic DNA.

Products for Step 1: Prepare Sample

 

BloodPrep® DNA Chemistry for Cultured Cells and Blood
BloodPrep® DNA Chemistry is designed to rapidly isolate DNA from fresh or frozen blood from any animal species, tissue-cultured cells, or buccal swabs. The protocol is designed for use with the Applied Biosystems® 6100 Nucleic Acid PrepStation and 6700 Automated Nucleic Acid Workstation.

Literature

Product Bulletins

Manuals & Protocols

Posters

Application Notes

Regulatory Status: For Research Use Only. Not for use in diagnostic procedures.

Select Language