Transporter Products

Let Invitrogen help you evaluate your compound’s transporter interactions.  With a comprehensive offering of transporter-qualified hepatocytes, vesicles, kits and services, we can extend your efforts and accelerate your answers, helping you in the prediction of bioavailability and clearance of your compound, as well as the potential for drug-drug interactions and potential toxicities.

Unique in vitro models to facilitate understanding:
  • GenoMembrane Transporter Vesicles
  • Transporter-qualified hepatocytes

GenoMembrane ATP-binding Cassette (ABC) Transporter Vesicles

GenoMembrane ATP-binding cassette (ABC) transporter vesicles allow the investigation of possible interactions between specific ABC transporters and your test compounds.

Transporter-Qualified Hepatocytes

Primary hepatocytes are effective tools for the in vitro evaluation of metabolism, drug-drug interactions, hepatotoxicity, and transporter assessment.  At Invitrogen, our hepatocyte isolationists are extensively trained in proper techniques to ensure optimal cell health.  As a result, GIBCO® hepatocytes have high viabilities, in vivo-like enzyme expression levels, and if released as plateable cells, excellent confluencies that contribute to polarization and functioning cell-cell contacts.

  • Contain functional membrane receptors and transporters
  • Facilitate effective transporter uptake and basolateral efflux (plated) experiments
  • Have stringent release specs: ≥80% viability and ≥80% confluency (plated cells)

Learn more about Transporter-Qualified Hepatocytes