ADME/Tox
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Invitrogen offers a collection of in vitro ADMETox tools and custom services for drug discovery and development, including GIBCO® hepatocytes, microsomes, and transporter products to help you determine the metabolic and safety profiles of lead candidates.
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ADME/Tox Products
Transporter ProductsB-CLEAR® Hepatic Transport Kits, GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes
Nuclear Receptor ADME AssaysOur LanthaScreen® PXR (SXR) and CAR Competitive Binding Assays contains all the reagents you need to conduct compound affinity testing
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Liver MicrosomesLarge pooled lots for long-term studies tested for select CYP450 & phase II enzyme activities
P450 AssaysFluorescent substrates and recombinant enzymes to evaluate your compound’s potential impact on P450 activity
hERG AssaysPerform cardiac safety screening with biochemical or cellular assays to identify potential hERG channel blockers
G-Protein Coupled Receptor Cellular ADME AssaysAvoid off-target effects with our GPCR toxicity panel of validated cellular assays for selectivity screening
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