Biochemical Kinase Assays

In vitro assays and screening technologies

As the drug discovery community escalates its efforts to develop kinase inhibitors, so the demand for robust assay technologies to identify lead compounds increases. At Invitrogen we have developed a variety of pre-configured fluorescent assay solutions to address HTS, hit confirmation and lead optimization programs.
Assay Technology
Application
LanthaScreen™ Kinase Activity Assays
Ideal primary screening technology due to lack of compound interference; validated for over 200 kinases

Adapta™ Universal Kinase Assays


Ideal for difficult to assay targets where high sensitivity and reduced compound interference are desired; validated specifically for lipid kinases

New! LanthaScreen™ Eu Kinase Binding Assays
Ideal for primary or secondary screening of unactivated or low-activity kinase targets due to direct binding readout. Also ideal for kinases with no known substrate.  Validated for over 200 kinases
Z´-LYTE® Kinase Assay
Ideal for secondary screening, hit validation, and profiling; validated for over 250 kinases.  Primary for SelectScreen™ Kinase Profiling Service.
Omnia® Kinase Assays
Ideal for mechanistic studies and measuring kinase activity in cell lysates. Simple mix-and-read fluorescence-based assay allows measurements in real time (kinetics).
NDP Sensor
Ideal universal, real-time kinetic kinase assay platform at a very low price per well.