Target & Lead Identification & Validation

Advance your drug discovery pipeline today using our comprehensive portfolio of products and services to investigate the major druggable target classes: kinases, GPCRs, nuclear receptors, and ion channels. Our offerings span everything from high-quality reagents for basic research and assay development, to validated biochemical and cell-based assays, and world-class profiling and screening services. For pharmaceutical research and discovery, your target is our aim.

Choose your application

	Kinase Biology Empower your kinase research with the broadest set of proteins, biochemical assays, and cell-based assays for discovery, assay development, and HTS.			Pathway Biology Analyze complex signal transduction pathways in a live cell format with our cell-based assays for Pathway Analysis.

	G-Protein Coupled Receptor Biology Interrogate difficult GPCRs with our cellular tools featuring Tango™, GeneBLAzer®, ion indicator, and division-arrested assay technologies.			Epigenetics Tools Investigate epigenetic enzymes and substrate modifications with our flexible set of cellular and biochemical tools.

	Nuclear Receptor Biology Enabling nuclear receptor screening with purified proteins, competitive binding kits, coregulator interaction assays, and validated cell-based assays.			Ion Channel Biology Screen compounds that modulate ion channels with our fluorescence-based indicators, including fluo-4 and voltage sensor probes.