Target-based ADME/Tox Assays

Invitrogen offers a collection of target-based ADME/Tox assays for drug discovery and development to help you determine the metabolic and safety profiles of lead candidates.

Featured Categories

Nuclear Receptor ADME Assays

Our LanthaScreen® PXR (SXR) and CAR Competitive Binding Assays contains all the reagents you need to conduct compound affinity testing

PCR-Based Drug Discovery Assays

Analyze drug discovery-related genes using our real-time PCR arrays

Transporter Products

GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes

Toxicology Products

Assays to identify indicators of both biochemical and cellular toxicity

P450 Assays

Fluorescent substrates and recombinant enzymes to evaluate your compound’s potential impact on P450 activity

hERG Assays

Perform cardiac safety screening with biochemical or cellular assays to identify potential hERG channel blockers

G-Protein Coupled Receptor Cellular ADME Assays

Avoid off-target effects with our GPCR toxicity panel of validated cellular assays for selectivity screening