Target-Based ADME/Tox Assays

Life Technologies offers a collection of target-based ADME/Tox assays for drug discovery and development to help you determine the metabolic and safety profiles of lead candidates on a high throughput scale.

Featured Target-Based ADME/Tox Assay Categories

P450 Assays

Fluorescent substrates and recombinant enzymes to evaluate your compound’s potential impact on P450 activity

 Transporter Products
GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes to facilitate the prediction of your compounds modulation of transport enzyme activity
 
hERG Assays

Perform cardiac safety screening with biochemical or cellular assays to identify potential hERG channel blockers

 Nuclear Receptor ADME Assays

Our LanthaScreen® PXR (SXR) and CAR Competitive Binding Assays contains all the reagents you need to conduct compound affinity testing

 
G-Protein Coupled Receptor Cellular ADME Assays

Avoid off-target effects with our GPCR toxicity panel of validated cellular assays for selectivity screening

 Toxicology Products

Assays to identify indicators of both biochemical and cellular toxicity

 
PCR-Based Drug Discovery Assays

Analyze drug discovery-related genes using our real-time PCR arrays

   

SelectScreen® Services

Expect more with P450 and hERG screening services


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ADME/Tox eNews

ADME/Tox News - insight into products, techniques, promotions and events

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ADME/Tox Resources

Scientific references, protocols, videos, and much more


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For Research Use Only. Not for use in diagnostic procedures.