New Products and Services for Drug Discovery
 |
Move your research forward in confidence by employing the newest products and services for drug discovery aimed at your target. Whether your research involves GPCRs, Kinases, Nuclear Receptors, or Ion Channels, Invitrogen has biochemical and cellular solutions for your needs. Learn more about our entire portfolio of products and services for drug discovery |
Newly Launched Products and Services
New ROR cell-based assay kit
Gain more insight into novel ROR gamma ligands with biochemical and cellular assays.
Our complete set of reagents for ROR gamma research includes purified proteins, biochemical assays and now an ROR gamma-specific cellular assay. Also available are proteins and biochemical assays for ROR alpha.
Division arrested cells - GeneBLAzer® ROR gamma UAS-bla HEK Cellular Assay
Kinase Biology
New kinase proteins available
DDR1 is a receptor tyrosine kinase activated by collagen and is reported to regulate adhesion, cell migration and other cellular processes. This kinase is validated in the LanthaScreen® Eu Kinase Binding Assay.
ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. This kinase is validated in the LanthaScreen® Eu Kinase Binding Assay.
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates.
Search the human kinome for a list of available kinase proteins.
Screening and Profiling Services
SelectScreen® Kinase Profiling Service
14 new assays available for profiling your compounds against your favorite kinases. With more than 300 kinase assays available for profiling, we are sure to have your target/s of interest.
Newly launched kinases include:
BMPR1A (ALK3)
CLK4
DNA-PK
HIPK3
MKNK1 (MNK1)
TGFBR1 (ALK5)
TXK
To start your next project today, view our complete list of kinases available for profiling.
SelectScreen® Cell-based Pathway Profiling Service
9 new assays available for your next pathway profiling project. With more than 70 assays available for profiling, we are sure to have your pathway of interest.
Newly launched cell lines include:
| Pathway/Target | Cell Line |
| B Cell Receptor | NFAT-bla RA-1 |
| MAPK | c-fos-bla HEK 293T |
| MAPK | c-fos-bla ME-180 |
| MAPK/MEK/B-raf | AP1-bla A375 |
| Glucocorticoid Receptor | MMTV-bla HeLa |
To start your next project today, view our complete list of pathway assays available for profiling.
 |
Recently Launched Products and Services
TR-FRET Assay Reagents
New Europium assay reagents available
Get choice and flexibility from your Europium assay reagents supplier. Now you can access the same reagents, at a better price – and try them for free.
View our complete list of TR-FRET assay reagents
See how our europium reagents compare to your current supplier. See if you qualify for an evaluation.
New Elite Tb-anti-His-Tag antibody
If your current source of Tb-anti-His-Tag antibody isn’t optimal for your assay application, now you can access our Elite Tb-anti-His-Tag antibody with a new, improved formulation to increase the robustness of your assay.
Nuclear Receptor Biology
Now you can screen the whole PPAR family – alpha, beta, and gamma
Completing the PPAR family of cell-based assays, now you can screen PPAR alpha in an easy, off-the-shelf cellular assay system. Also available for the PPAR family are PPAR delta and gamma cellular systems, as well as biochemical systems for all three isoforms.
View our entire list of cellular assays and biochemical assays for nuclear receptors
Kinase Biology
New kinase proteins available
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis. This kinase is validated using the Adapta® assay.
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrance ser/thr kinases which in response to bone morphogenic proteins phosphorylates intracellular SMADs. This kinase is validated with the LanthaScreen® Eu Kinase Binding Assay.
Search the human kinome for a list of available kinase proteins.
New Europium assay reagents available
Get choice and flexibility from your Europium assay reagents supplier. Now you can access the same reagents, at a better price – and try them for free.
- Eu-Streptavidin
- Eu-anti-biotin
- Eu-anti-DYKDDDK
View our complete list of TR-FRET assay reagents
See how our europium reagents compare to your current supplier. See if you qualify for an evaluation.
New Elite Tb-anti-His-Tag antibody
If your current source of Tb-anti-His-Tag antibody isn’t optimal for your assay application, now you can access our Elite Tb-anti-His-Tag antibody with a new, improved formulation to increase the robustness of your assay.
Nuclear Receptor Biology
Now you can screen the whole PPAR family – alpha, beta, and gamma
Completing the PPAR family of cell-based assays, now you can screen PPAR alpha in an easy, off-the-shelf cellular assay system. Also available for the PPAR family are PPAR delta and gamma cellular systems, as well as biochemical systems for all three isoforms.
- GeneBLAzer® PPAR alpha cellular assay
- GeneBLAzer® PPAR delta cellular assay
- GeneBLAzer® PPAR gamma cellular assay
View our entire list of cellular assays and biochemical assays for nuclear receptors
Kinase Biology
New kinase proteins available
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis. This kinase is validated using the Adapta® assay.
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrance ser/thr kinases which in response to bone morphogenic proteins phosphorylates intracellular SMADs. This kinase is validated with the LanthaScreen® Eu Kinase Binding Assay.
Search the human kinome for a list of available kinase proteins.
|