Bacterial RNA Extraction

Effective cell lysis is a required first step for extraction of good yields of high quality RNA. Yeast and many bacterial strains can be difficult to disrupt because, unlike eukaryotic cells, they are protected by cell walls. Mechanical disruption or enzymatic pretreatment are typically used to thoroughly disrupt bacterial and yeast cells for RNA isolation. We offer a wide selection of RNA purification reagents and kits that are optimized to provide maximum yield, purity, and integrity from bacteria and yeast in several format options.

Which Bacterial RNA Extraction Kit is Right for You?

  No lysis procedures Fast & easy, 20 min HTP, 45 min Ideal for hard-to-lyse gram + bacteria
Top Seller   yes    
Includes specialized beads for cell lysis No No Zirconia beads Zirconia beads
Isolation method High purity organic extraction
(requires alcohol precipitation)
Fast, convenient silica column Scalable, flexible format with magnetic beads Highest purity & convenience; includes organic extraction & silica column
(no precipitation required)
Prep time 1 hour 20 minutes 45 minutes 1 hour
Amount of starting material Up to 1 x 108 cells Up to 1 x 109 cells Up to 0.3 g solid samples or 175 µl liquid samples Up to 109 cells
High throughput compatible     yes  
Kit size 100 preps 50 preps 100 preps 50 preps
Price per prep $4.43 $4.50 $5.24 $7.58
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