DNA Extraction From Blood

Rapid and Efficient DNA Extraction From Blood

Genotyping has become an essential application in clinical trials for pharmacogenomics studies. The emergence of pharmacogenomic centers of excellence has resulted in an increasing need for purification of high-quality genomic DNA from large volumes of blood. Since samples are collected and shipped worldwide, every sample may require different storage and shipping conditions. Choosing the right genomic DNA extraction from blood is important based on your needs and expected end results. Life Technologies offers a wide range of kits designed for DNA extraction from blood or serum samples at the purity and scale you need.

Which DNA Extraction From Blood Kit is right for you?

Cost effective, designed for blood and sera Rapid processing for scale and automation Most versatile, can handle variety of sample types Large volume processing (10 mL), ideal for tough and degraded samples
 
 
Recommendation Most cited Fastest protocol Top seller  
Blood Sample Type Whole blood (fresh), serum Whole blood (fresh, frozen, or treated blood [e.g., EDTA, citrate, ACD, heparin])   Whole blood (fresh, frozen, or treated blood [e.g., EDTA, citrate, ACD, heparin]), buffy coat, bone marrow   Whole blood (fresh, frozen, repeatedly frozen/thawed and archived samples, or treated blood [e.g., EDTA, citrate, ACD, heparin] and degraded samples)
Starting Material 500 µL blood 10–20 µL serum
50–100 µL blood
  Up to 200 µL blood** (single pass)
Up to 1 mL blood (multiple pass)
  3–10 mL blood
Yield 10-20 µg DNA Up to 600 ng DNA   3–10 µg DNA for 200 µL   60–300 µg DNA
Protocol Time 30–60 min <15 min   <20 min   40 min
Isolation Technology Organic extraction ChargeSwitch® Chemistry, beads, 96-well plates   Silica Spin Column   Magnetic bead
High Throughput Compatability No Yes   No (option available)   No (option available)
High Throughput / Automation ChargeSwitch® Direct 96 gDNA Kit   PureLink® Pro 96 Genomic DNA Purification Kit   GeneCatcher™ gDNA Automated Blood Kit (96 x 10 mL)
Kit Size Available 100 mL 50 preps, blood
960 preps, blood
50 preps, serum
10 preps
50 preps
250 preps
  96 preps (for samples 0.3–1 mL)
200 mL (for samples 3–10 mL)
Cost/Prep $1.71 $2.61   $2.26   $4.52*
Order Now Order Now   Order Now   Order Now

*based on 3 mL sample
**Additional Pro K and lysis buffer needed.

Working in a GMP Laboratory?

The ChargeSwitch® EasyPlex™ is for you! ChargeSwitch® EasyPlex™ has licensing suitable for the standardized testing market. These kits are labeled with GPR (general purpose reagent), and therefore can be validated for use in standard operating procedures (SOPs) by clinical labs.

Learn more about ChargeSwitch® EasyPlex™

Resources

Other Products of Interest
In addition to DNA and RNA isolation products, Life Technologies offers an expansive portfolio of solutions for analysis and quantitation of tissue and cultured cell genomic DNA.
Protocols

 

For Research Use Only. Not for use in diagnostic procedures.