Filter Recommendations for Use With SYBR® Safe DNA Gel Stain

The table below lists recommended filters for specific gel documentation systems. If your system is not listed, contact the manufacturer for recommendations. Note that the excitation and emission spectra of SYBR® Safe DNA gel stain are very similar to those of SYBR® Green I, SYBR® Green II, and SYBR® Gold dyes, as well as fluorescein (FITC). Therefore, filters appropriate for these dyes can also be used. A camera filter is not required with the Safe Imager™ blue-light transilluminator; the amber filter provided with the instrument serves this purpose.

InstrumentManufacturerExcitation SourceEmission Filter
Polaroid CameraPolaroidUVSYBR® Safe photographic filter (S37100)*
FCR-10PolaroidUV#3-4218
AlphaImagerAlpha Innotech302 nmSYB-500
AlphaDigiDoc RTAlpha InnotechUV transilluminator 
Shroud, Camera StandAlpha InnotechUV transilluminator 
DE500 or DE400 light cabinet 2.17" diam.Alpha InnotechUV transilluminatorSYB-100
DE500 or DE400 light cabinet 2" diam.Alpha InnotechUV transilluminatorSYB-500
VersaDoc Imaging SystemsBio-RadBroadband UV520LP
Molecular Imager FX SystemsBio-Rad488 nm530 DF 30
Gel Doc SystemsBio-Rad302 nm520DF30 (#170-8074)
Typhoon 9400/9410GE Healthcare488 nm520 BP 40
Typhoon 9200/9210/8600/8610GE Healthcare488 nm526 SP
FluorImagerGE Healthcare488 nm530 DF 30
StormGE HealthcareBlue (fluorescence mode) 
ImageMaster VDS-CLGE HealthcareTransmissionUV Low
Ultracam/Gel ImagerUltra-LumUVYellow Filter (#990-0804-07)
Omega SystemsUltra-LumUV520 nm
FOTO/Analyst Express/Investigator/Plus/LuminaryFotodyneUVFluorescent Green (#60-2034)
FOTO/Analyst Express/Investigator/Plus/LuminaryFotodyneUVFluorescent Green (#62-4289)
FOTO/Analyst MinivisionaryFotodyneUVFluorescent Green (#62-2535)
FOTO/Analyst ApprenticeFotodyneUVFluorescent Green (#60-2056)
FUJI FLA-3000FUJI Film473 nm520LP
BioDocIt/AC1/EC3/BioSpectrumUVP302 nmSYBR® Green (#38-0219-01)
or
SYBR® Gold (#38-0221-01)
Gel LogicKodakUV 535535 nm WB50
Mini BIS/Mini BIS ProDNR BioimagingUV 320Yellow
Compact BISDNR BioimagingUV 320Orange
Syngene InstrumentsSyngeneUV500–600 nm Shortpass filter

*Filter available from Molecular Probes/Invitrogen
Optional filters available from respective manufacturer