Genomic DNA Purification Overview
| Application | Product | When to use | High-throughput/automation options | |
|---|---|---|---|---|
| Tissue and cells | ||||
| ChargeSwitch® gDNA | High-quality DNA, high-throughput | iPrep™ ChargeSwitch® gDNA Kits | ||
| ChargeSwitch® gDNA Buccal Cell Kit | ||||
| ChargeSwitch® Direct gDNA | Sample lysis to PCR in one well (nonmagnetic beads) | ChargeSwitch® Direct 96 Plates | ||
| ChargeSwitch® EasyPlex™ | GMP for standardized testing labs (nonmagnetic beads) | ChargeSwitch® EasyPlex™ Plates | ||
| PureLink™ Genomic DNA Kits | Robust performance in familiar spin-column format | PureLink™ 96 Genomic DNA Kit Plates | ||
| DNAzol® | Isolation of genomic DNA from blood (mammalian tissues, cells) | |||
| Bone marrow
| Dynabeads® DNA DIRECT™ Blood Kit | 15 minute protocol, sample lysis to PCR in one tube, processes 100 isolations from 100 µL of blood each sample, scalable (<10 µL sample up to >500 µL sample), high-throughput compatible | Dynabeads kit at left in conjunction with: DynaMag™-96 Side Magnet &/or DynaMag™-96 Bottom Magnet | |
| Cerebrospinal fluid, bile, feces, algae, fungi, soil samples. | Dynabeads® DNA DIRECT™ Kit | 10 minute protocol, small samples, high-quality DNA, high-throughput compatible, sample lysis to PCR in one tube. | Dynabeads kit at left in conjunction with: DynaMag™-96 Side Magnet &/or DynaMag™-96 Bottom Magnet | |
| Frozen blood. | Dynabeads® DNA DIRECT™ Blood Kit | 15 minute protocol, sample lysis to PCR in one tube, processes 100 isolations from 100 µL of blood each sample, scalable (<10 µL sample up to >500 µL sample), high-throughput compatible | Dynabeads kit at left in conjunction with: DynaMag™-96 Side Magnet &/or DynaMag™-96 Bottom Magnet | |
| Blood and serum | ||||
| ChargeSwitch® gDNA Blood and Serum Kits | Small volume, bead sample processing; high-performance down-stream processing (magentic beads) | ChargeSwitch® Direct 96 gDNA Kit | ||
| ChargeSwitch® Direct gDNA | Sample lysis to PCR in one well (nonmagnetic beads) | ChargeSwitch® Direct 96 gDNA Kit | ||
| ChargeSwitch® EasePlex™ | GMP for standardized testing labs (nonmagnetic beads) | ChargeSwitch® EasePlex™ Plates | ||
| GeneCatcher™ | Large volumes of human blood (magentic beads) | iPrep™ PureLink™ gDNA Blood Kit | ||
| DNAzol® BD | Isolation of genomic DNA from blood | |||
| Forensic | ||||
| ChargeSwitch® Forensic DNA and ChargeSwitch® gDNA Normalized Buccal Cell Kit | Optimized for STR Analysis and for poor or environmentally degraded samples (magenetic beads) | iPrep™ ChargeSwitch™ Forensic Kit and ChargeSwitch® gDNA Normalized Buccal Cell Kit | ||
| Bacteria | ||||
| ChargeSwitch® gDNA Mini Bacteria | Gram-positive and Gram-negative bacteria (magnetic beads) | |||
| Virus | ||||
| PureLink™ Viral RNA/DNA | Viral RNA or DNA from cell-free samples (spin column) | PureLink™ 96 Viral RNA/DNA iPrep™ PureLink™ Virus Kit | ||
| ChargeSwitch® EasyPlex™ viral RNA/DNA | For viral detection/genotyping from 30ul of cell-free sample | ChargeSwitch® EasyPlex™ Viral RNA/DNA Plates | ||
| Plant | ||||
| ChargeSwitch® gDNA Plant | Plant leaf or seed samples (magentic beads) | ChargeSwitch® gDNA Plant 960 Kit | ||
| PureLink™ Genomic Plant | Chloroplasts and low-abundance DNA plant samples (spin column) | |||
| Plant DNAzol® | Isolation of genomic DNA from plant material |
All ChargeSwitch® Kits All PureLink™ Kits All iPrep™ Kits and Instruments