GeneArt® Gene Synthesis
 | The GeneArt® Gene Synthesis service consists of chemical synthesis, cloning, and sequence verification of virtually any desired genetic sequence. You will receive a bacterial stab and/or purified plasmid containing your synthesized gene—ready for downstream applications. |
Gene Synthesis at Record Speed |
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Fast, simple alternative to traditional cloning
Whether you have limited cloning experience or simply want to save time, the GeneArt® Gene Synthesis service helps you move your ideas from the planning stage to the laboratory more quickly. Benefit from our experience in successfully producing over 180,000 constructs for customers as diverse as large pharmaceutical companies, biotechnology start-ups, and basic research institutions. The comparison shown in the figure below highlights the time and effort saved compared to traditional cloning.
Applications for synthetic genes
- Maximizing expression yields
- Gaining access to genes which are hazardous or otherwise hard to obtain
- Enhancing flexibility in design of gene constructs
- Increasing efficacy of gene therapy vectors or gene products such as vaccine candidates or engineered proteins
- Accelerating approval by regulatory authorities
- Creating new intellectual property
Benefits of GeneArt® Gene Synthesis
- Flexible, custom process: Obtain the exact sequence you need in the vector of your choice—including challenging, complex constructs and custom vectors.
- Maximized protein yield: Optional sequence processing with GeneOptimizer® software generates sequence variants with enhanced mRNA stability and translational efficiency.
- Rapid synthesis and assembly: Standard turnaround times start at 10 business days (depending on sequence length). Accelerated options are also available.
- Excellent accuracy: All custom synthesized genes are sequenced as part of our ISO 9001:2008–certified quality management system; we only ship constructs with exact sequence agreement.
- Economical: The cost of the GeneArt® Gene Synthesis service rivals costs that would be incurred to purchase the oligonucleotides and molecular biology reagents required for gene synthesis. And then there is your time to consider.
- Efficient: Save time and labor by outsourcing your gene synthesis and cloning so you can focus on your research.
From its inception, the GeneArt® Gene Synthesis service has focused on automating the gene synthesis process. The aim was clear—to make gene synthesis a fast and reliable technology. Over the years, we have focused our scientific expertise and invested heavily in the development of a proprietary process technology that meets the criteria of even the most demanding customers—the GeneAssembler® gene synthesis platform.
Today, the GeneArt® Gene Synthesis service offers high-throughput gene assembly on an industrial scale. Using optimized, highly parallel processes, the GeneAssembler® platform achieves turnaround times as fast as two weeks for a fully cloned gene with very high reliability. Moreover, our scientists have gathered vast experience in the synthesis and production of virtually all types and sizes of genes, sequences, operons and even genomes.
GeneArt® Services provides a full range of cloning, optimization, and protein expression options to serve many areas of biological research and production.
GeneArt® Gene Synthesis Process
| Submitted DNA sequences are designed by our team of highly skilled scientists to include/exclude restriction enzyme sites and translation elements as requested, and are optionally optimized using our GeneOptimizer® software for maximum protein production. |
