Transfection Reagent Selection Chart

The Invitrogen™ suite of transfection products has been developed for highly-efficient delivery of nucleic acids into different cell types while maintaining the highest post-transfection cell viability.  These products support a full spectrum of transfection applications that rely on transfection reagents in all areas of basic research, drug discovery and experimental therapeutics.

TransfectsTransfection ReagentExpressesApplicationsComments
PlasmidsLipofectamine® LTX with PLUS™ Reagent
  • Gene/Protein
  • shRNA
  • miRNA
  • Protein Expression
  • RNAi
  • High efficiency
  • High protein expression
  • Very gentle to cells
siRNALipofectamine® RNAiMAX 
  • RNAi
  • Synthetics only
  • Highest knockdown
Plasmids & siRNALipofectamine® 2000
  • Genes
  • shRNA
  • miRNA
  • Cotransfection
  • High Throughput
  • Highest efficiency
  • High protein expression
  • For robust cells
Plasmids, siRNA & ProteinNeon® Transfection System
  • Gene/Protein
  • shRNA
  • miRNA
  • Protein Expression
  • RNAi
  • High efficiency & viability due to unique pipette design
  • Efficient gene delivery into primary & stem cells
PlasmidsFreeStyle™ MAX
  • Protein
  • BioProduction
  • Large scale protein production