Plasmid DNA Transfection

To obtain efficient gene transfer by transfection, plasmid DNA can be complexed with lipid reagents to mediate efficient delivery into the cell's nucleus. This process is essential for subsequent protein expression of the gene of interest. Plasmids are small circular DNA molecules that naturally occur in bacteria, and are actually used by the bacteria to transfer genetic information. The mechanism of adding a DNA Plasmid into a mammalian cell is known as plasmid transfection.

Invitrogen offers a wide range of transfection reagents for your specific needs.  For cell types specific protocols, please refer to Transfection Selection Tool.

Which Plasmid DNA Transfection Reagent is Right for You?

  Value reagent for common cell types Most cited & versatile reagent for a wide range of cell types Most efficient reagent for plasmid delivery. Potent & low-cytotoxicity High-efficiency electroporation for all cell lines
Top Selling Format Catalog #18324-012 - 1 mL Catalog #11668-019 - 1.5 mL Catalog #15338-100 - 1 mL Catalog #MPK5000S
Sample Type Plasmid DNA Plasmid DNA
RNA (e.g. siRNA, miRNA)
RNAi plasmids
Plasmid DNA
RNAi plasmids
Plasmid DNA
RNA (e.g. siRNA, miRNA)
Protein
RNAi plasmids
Transfection Efficiency for Common Cell Types Standard High Superior Maximal
Best for Primary & Stem Cells yes
Publications (Feb 2012) 8,091 22,711 631 201
Price / 0.1 mL $24 $26 $44 $6.50 per transfection
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