Gibco® Growth Factors
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More validation, more stability, more value. |
Select your Growth Factor, Cytokine or Chemokine
Featured Products
 | Recombinant Activin A Activin A plays a role in hormone secretion, neuronal survival, and proliferation. Activin A also plays a role in the differentiation of many cell types including hematopoietic and neuronal cells. |  | Recombinant IL-17F The most notable role of IL-17F is it involvement in inducing and mediating pro-inflammatory responses in asthma. See all recombinant IL-17F. | |||
 | Recombinant BMP-4 This BMP family member plays an important role in the differentiation of various cell types, including embryonic stem cells (ESCs), epithelial cells, hematopoietic cells, induced pluripotent stem cells (iPSCs), mesenchymal cells, and neuronal cells. |  | Recombinant Thrombopoietin (TPO) A humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. | |||
 | Recombinant BMP-7 BMP-7 plays a role in the differentiation of mesenchymal cells into bone and cartilage. BMP7 may also be involved in bone homeostasis. |  | Recombinant TGF-β2 TGF-β2 binds the transforming growth factor-β receptor and plays a role in regulation of cell growth and proliferation. It may be involved in mesenchymal- More epithelial cell interactions during development. |
Growth Factor Validation & Quality
Figure 1. High purity. SDS-PAGE analysis of purified recombinant human RANTES (Cat. No. PHC1054) and mouse SCF (Cat. No. PMC2114). | Figure 2. More bioactive protein due to exceptional refolding techniques. Proliferation of MO7e cells in response to SCF from GIBCO® and the competitor (Cat. No. PHC2115). As illustrated by the lower ED50, less GIBCO® SCF is required to yield a response. | |
Figure 3. Structural homogeneity. The SDS-PAGE gel was run on Human BMP-2 (Cat. No. PHC7145) under reducing (lanes 2 and 3) and non-reducing (lanes 4 and 5) conditions. Under non-reducing conditions, BMP-2 is seen as a dimer, consistent with biologically active BMP-2. | Figure 4. Calcium flux confirms expected biological response. Calcium flux activation was observed by stimulating Fura-2–loaded rat PMNs with the GIBCO® chemokine CINC-2β (Cat. No. PRC1564). | |
Figure 5. High bioactivity of FGF-basic. Proliferation of Balb/3T3 cells in response to FGF (Cat. No. PHG0024) is demonstrated. GIBCO® FGF-basic is more active than the competitor’s FGF-basic. | Figure 6. Protease activity confirms protein functionality. Enzymatic activity of Kallikrein 4 (KLK4) was measured by its ability to cleave fluorogenic peptide substrate Boc-Val-Pro-Arg-AMC. The end product is measured using fluorescence excitation and emission wavelengths of 380 nm and 460 nm, respectively. |
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Growth Factors for Your Clinical Research
Gibco® Cell Therapy Systems™ (CTS™) growth factors offer:
- ISO 13485 quality
- High purity
- High activity
For research use only. It is not intended for animal or human therapeutic or diagnostic use.
