3D Cell Culture Systems

Geltrex® LDEV-Free Matrix Products

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  • Safe to use in all cell culture experiments – Geltrex® products are free of the lactate dehydrogenase-elevating virus (LDEV) making them ideal for all types of cell culture and
    mouse in vivo research
  • Reduce lot screening - consistent protein concentration from lot-to-lot and functional testing on each lot helps to decrease variability in your cell culture experiments

View the table below to order your Geltrex® product with the new catalog number.

Choose your Geltrex® Matrix:

Old SkuNew SkuProduct Name Size
12760013A1413201Geltrex® LDEV-Free Reduced Growth Factor Basement Membrane Matrix1 ml
12760021A1413202Geltrex® LDEV-Free Reduced Growth Factor Basement Membrane Matrix
5 ml
A1048001A1413301Geltrex® LDEV-Free hESC-qualified Reduced Growth Factor Basement
Membrane Matrix		1 ml
A1048002A1413302Geltrex® LDEV-Free hESC-qualified Reduced Growth Factor Basement
Membrane Matrix		5 ml

Use Geltrex® Matrix in all your cell culture applications

Geltrex® Matrix is a soluble form of reduced growth factor (RGF) basement membrane extract (BME) purified from murine Engelbreth-Holm-Swarm tumor. Historically these preparations have contained the lactate dehydrogenase-elevating virus (LDEV) which does not impact the performance of the material but may be of concern in certain applications such as xenografts or other clinically focused research. New manufacturing methods are now available which allow for the removal of this virus. The resulting LDEV free material is tested using PCR methods to confirm that the material is virus free.

Reduced lot screening

Lot-to-lot differences in BME protein concentration can cause variability in cell culture experiments. Each lot of Geltrex® Matrix is tested to determine protein concentration.

In addition, Geltrex® Matrix is tested for its ability to support endothelial tube formation from cryopreserved endothelial cells. Human ESC-qualified lots of Geltrex® Matrix have been tested for their ability to support feeder-free culture of human embryonic stem cells (hESCs) with StemPro® hESC SFM.

 Technical Resources

Applications

For research use only. Not for human or animal therapeutic or diagnostic use.

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