Geltrex® LDEV-Free Matrix Products
View the table below to order your Geltrex® product with the new catalog number.
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Use Geltrex® Matrix in all your cell culture applications
Geltrex® Matrix is a soluble form of reduced growth factor (RGF) basement membrane extract (BME) purified from murine Engelbreth-Holm-Swarm tumor. Historically these preparations have contained the lactate dehydrogenase-elevating virus (LDEV) which does not impact the performance of the material but may be of concern in certain applications such as xenografts or other clinically focused research. New manufacturing methods are now available which allow for the removal of this virus. The resulting LDEV free material is tested using PCR methods to confirm that the material is virus free.
Reduced lot screening
Lot-to-lot differences in BME protein concentration can cause variability in cell culture experiments. Each lot of Geltrex® Matrix is tested to determine protein concentration.
In addition, Geltrex® Matrix is tested for its ability to support endothelial tube formation from cryopreserved endothelial cells. Human ESC-qualified lots of Geltrex® Matrix have been tested for their ability to support feeder-free culture of human embryonic stem cells (hESCs) with StemPro® hESC SFM.
For research use only. Not for human or animal therapeutic or diagnostic use.