Exosome Research Products
![]() | These small (30-120nm) extracellular vesicles aren’t cellular “trash bags” after all. Now that exosomes have been identified in a wide range of body fluids, they are thought to play a role in an unknown number of biological functions. What’s the mechanism of exosome formation? What do they contain? How can they best be isolated and studied? The field of exosomes research is truly captivating, with a need for a range of specific tools and technologies. |
Isolation & Purification ProductsIsolating exosomes used to be a tedious, nonspecific, and difficult process, typically involving ultracentrifugation. With the total exosome isolation kits, you can now enrich for intact exosomes starting from cell culture media or serum. The protocol can be scaled to match your sample size. To isolate specific exosome subpopulations, total exosome enrichment from cell culture is followed by the use of the new Dynabeads® Human CD63-specific purification system. Alternatively, you can purify exosomes using the new Dynabeads® Streptavidin purification system in combination with your choice of a biotinylated specific antibody. |
Characterization & Analysis ProductsOnce exosomes are bound with either the new Dynabeads® Human CD63 or Dynabeads® Streptavidin purification systems, you can detect by using common laboratory techniques such as flow cytometry, electron microscopy, or western blot analysis. Do you want to recover total RNA or both total RNA and proteins from your sample? The Total Exosome RNA and Protein Isolation Kit is designed for studies of RNA expression (specifically miRNA), processing, and function. Dynabeads® magnetic separation technology is widely used for immunoprecipitation. Now you can even isolate proteins from pre-enriched exosomes using Protein A or Protein G coupled to Dynabeads® magnetic beads. |
Videos
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PublicationExosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. |





