Inflammatory Response Pathway | Life Technologies

Inflammatory Response Pathway

A protective response of cells to infection, inflammation involves the coordinated communication among different immune cells through an intricate cascade of molecular signals.

Life Technologies offers the best way to evaluate the right tools for your inflammatory research including antibodies, ELISAs, Luminex® multiplex assays, and growth factors for key targets in the inflammatory response signaling cascade.

Find MAPK signaling pathway primary antibodies, antibody pairs, ELISAs and Luminex® assays by protein:

Novex® Multiplex Panels

Target A–H

Target I–L

Target M–V

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Introductory Trial Offer

The Best Way to Put Your Pathway Research to the Test

For a limited time we are offering an introductory trial offer, the best way to evaluate tools for your Inflammation research, to keep your research a step ahead. Select any Novex® Inflammation pathway–related product on the page, and save 50%.

Use promotion code P923832 (US) or P923833 (Canada) when placing your order.*

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Recombinant Protein

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High bioactivity of FGF-Basic.

Proliferation of Balb/3T3 cells in response to FGF-Basic (Cat. No. PHG0024) is demonstrated. FGF-Basic is more active than the competitor’s FGF-basic.

ELISA Quantification

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Novex® ELISA kits provide reproducible results from lot to lot.

Individual production lots (A–K) of the IFN-γ Human ELISA Kit (Cat. No. KHC4021) were analyzed using 4 concentrations of control target protein (C1–C4). All 11 lots provided uniform sensitivity and low lot-to-lot variation (<20%).

Assay Precision

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Assay precision. Orange and gray bars each represent 24 replicates measured on separate days.

CVs in all cases were less than 10%. Data were generated using a Cytokine Human Magnetic 10-plex Panel (Cat. No. LHC0001M).

Inflammatory Protein Targets A–H

Target	Category	ELISA	Luminex® Assays
Aggrecan	Arthritis	KAP1461
Angiopoietin-2	Growth factors	KHC1641
BDNF	Growth factors		LHC7071
CD23	CD Markers	KAS0251
CD30 (soluble)	CD Markers		LHS6031
CD40L (soluble)	CD Markers	KHS4001
C-Reactive Protein	Acute Phase	KHA0031	LHP0031
E-cadherin	Cell Adhesion	991700
EGF	Growth factors	KHG0062 KHG0061	LHG0061
ELAM-1 (soluble)	Cell Adhesion	KHS2011
Eotaxin/CCL11	Chemokine	KAC2231	LHC2231
FGF basic	Growth factors	KHG0022 KHG0021	LHG0021 LMG0021
G-CSF	Cytokine	KMC2031 KHC2032 KHC2031	LPC2031 LHC2031 LMC2031
GDNF	Growth factors		LHC7041
GM-CSF	Cytokine	KMC2021 KHC2011	LHC2011 LMC2011 LRC2011
GRO-α	Chemokine		LHC1061
HGF	Growth factors	KAC2211	LHG0071

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Inflammatory Protein Targets I–L

Target	Category	Antibody Pairs	ELISA	Luminex® Assays
ICAM-1 (soluble)	Cell Adhesion		KHS5411
IFN-α	Cytokine		KHC4011 KMC4011	LHC4011
IFN-α (multi subtype)	Cytokine		KHC4032
IFN-β	Cytokine		KAC1201 KMC4041
IFN-γ	Cytokine	CHC1233 CAC1233 CMC4033 CSC4033	KAC1231 KMC4021 KMC4022 KMC4021C KBC1231 KHC4022 KHC4021 KPC4021 KHC4021C KSC4021 KSC4022 KPC4022 KRC4022 KRC4021	LHC4031 LMC4031 LPC4031 LRC4031
Ig	Isotyping		992000
IgG	Isotyping		991000
IL-10	Cytokine	CHC1323 CMC0103 CRC0103 CSC0103	KAC1321 KHC0102 KHC0101 KRC0101 KSC0102 KRC0102 KHC0103 KSC0101 KHC0104 KMC0101 KHC0101C KMC0102 KHC0104C KPC0101	LHC0101 LMC0101 LRC0101 LPC0101
IL-12	Cytokine	CMC0123	KMC0122 KMC0121 KPC0122 KPC0121 KRC0121 KMC0121C KRC0122	LPC0121
IL-12 (p40 & p70)	Cytokine		KHC0121 KHC0122 KAC1561
IL-12 (p40/p70)	Cytokine	CHC1563		LMC0121 LHC0121 LRC0121
IL-12 (p70)	Cytokine		KRC2371 KAC1568 KMC9121 KPC9121	LHC9121 LMC9121
IL-13	Cytokine	CMC2223 CRC0133	KRC0132 KMC2221 KRC0131 KHC0131 KHC0134 KHC0133 KHC0132	LHC0131 LMC0131
IL-15	Cytokine		KHC0151 KHC0152	LHC0151
IL-16	Cytokine		KHC0161	LHC0161
IL-17	Cytokine		KAC1591 KMC3021	LHC0171 LPC0171 LMC0171
IL-18	Cytokine		KHC0181 KSC0181 KMC0181 KRC2341

Target	Category	Antibody Pairs	ELISA	Luminex® Assays
IL-1B	Cytokine		KHC0019
IL-1ra	Cytokine	CHC1183	KAC1181	LHC0711
IL-1α	Cytokine		KAC1191	LHC0811 LMC0811 LRC0811
IL-1β	Cytokine	CMC0813 CHC1213	KAC1211 KHC0011 KHC0012 KMC0011 KRC0011 KMC0012 KRC0012 KHC0014 KRC0011C KMC0011C KHC0011C	LHC0011 LMC0011 LRC0011 LHC0013
IL-2	Cytokine	CHC1243 CRC0023 CSC1243	KMC0021C KAC1241 KMC0022 KPC0022 KMC0021 KPC0021 KRC0021 KRC0022 KHC0021 KHC0022 KHC0021C	LHC0021 LPC0021 LMC0021 LRC0021
IL-23	Cytokine	CMC2493 CHC2493	KMC0231
IL-23 Heterodimer	Cytokine		KHC0231
IL-2R	Cytokine		KHR0021	LHR0021
IL-3	Cytokine		KHC0031	LHC0031
IL-4	Cytokine	CMC0043 CSC1283 CHC1283	KAC1281 KRC0041 KPC0041 KMC0041 KMC0042 KHC0041 KSC0041 KHC0044 KHC0043 KSC0042	LMC0041 LHC0041 LPC0041 LRC0041
IL-5	Cytokine	CMC0053	KMC0051 KHC0052 KHC0051	LMC0051 LHC0051
IL-6	Cytokine	CHC1263 CMC0063 CRC0063	KHC0069 KAC1261 KPC0061 KRC0062 KMC0061C KRC0061 KRC0061C KMC0061 KMC0062 KHC0062 KHC0061 KHC0063 KHC0064 KHC0061C KHC0064C	LHC0061 LMC0061 LPC0061 LRC0061 LHC0063
IL-6R	Cytokine		KHR0061	LHR0061
IL-7	Cytokine			LHC0071
IL-8	Chemokine	CHC1303 CSC1223	KAC1301 KHC0081 KHC0082 KHC0084 KHC0083 KHC0081C KPC0081 KSC0082 KSC0081	LPC0081 LHC0081
IP-10	Chemokine	CHC2363	KAC2361	LHC1081 LMC1081 LPC1171M
KC	Chemokine	CMC1063	KMC1061	LMC1061
LIF-HILDA	Cytokine		KAC1351

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Inflammatory Protein Targets M–V

Target	Category	Antibody Pairs	ELISA	Luminex® Assays
MCP-1/CCL2	Chemokine	CHC1013	KHC1011 KRC1011 KHC1012 KMC1011 KRC1012 KMC1012	LMC1011 LHC1011 LPC1011
MCP-2/CCL8	Chemokine			LHC1111
MCP-3/CCL7	Chemokine			LHC1571
MIG/CXCL9	Chemokine			LHC1091 LMC1091
MIP-1α/CCL3	Chemokine		KAC2201	LHC1021 LPC1021 LMC1021
MIP-1β/CCL4	Chemokine	CHC2293		LMC1051 LPC1051 LHC1051
MIP-2	Chemokine		KRC1021 KRC1022
MIP-2	Chemokine
PAI-1	Acute Phase		KHC3071
PDGF-BB	Growth factors			LHG0041
p-Selectin (soluble)	Cell Adhesion		KHS2021
RANTES/CCL5	Chemokine		KHC1031 KHC1032 KAC1511 KRC1031 KMC1031	LPC1031 LHC1031 LMC1031
SAA (Serum Amyloid A)	Acute Phase	CHA2513	KMA0021 KHA0011 KAA0021 KHA0012 KHA0011C	LHP0061
TGF-ß1 (activated/treated)	Growth factors	CHC1683	KAC1688	LHG0121
TNFalpha	Cytokine		KRC3019
TNF-RI	Cytokine		KAC1761	LHC3021
TNF-RII	Cytokine		KAC1771	LHC3031
TNF-α	Cytokine	CHC1753 CMC3013 CRC3013 CSC1753	KAC1751 KHC3014 KRC3011 KRC3012 KHC3012 KMC3011C KMC3012 KHC3011 KPC3011 KHC3011C KMC3011 KHC3013 KPC3012 KSC3012 KHC3014C KSC3011 KRC3011C	LHC3011 LPC3011 LMC3011 LRC3011 LHC3013
VCAM-1 (soluble)	Cell Adhesion		KHT0601
VEGF	Growth factors	CHG0113	KMG0111 KMG0112 KHG0111 KHG0112	LHG0111 LMG0111

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Novex® Multiplex Panels for Inflammatory Proteins

Panel Name	Number of Targets	Targets	Polystyrene	Magnetic
Acute Phase 4-Plex Panel	4	β2 Microglobulin, Haptoglobin, CRP, Gc-globulin	LHC6006
Chemokine Human 10-Plex Panel	10	Eotaxin, GRO-α, IP-10, MCP-1, MCP-2, MCP-3, MIG, MIP-1α, MIP-1β, RANTES + Buffer kit	LHC6001
Chemokine Human 5-Plex Panel	5	Eotaxin, MCP-1, MIP-1α, MIP-1β, RANTES + Buffer kit	LHC0005
Chemokine Monkey 5-Plex Panel	5	IL-8, MCP-1, MIP-1α, MIP-1β, RANTES + Buffer kit	LPC0002
Chemokine Mouse 5-Plex Panel	5	IP-10, KC, MCP-1, MIG, MIP-1α + Buffer kit	LMC0005
Cytokine Human 10-Plex Panel	10	GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, TNF-α + Buffer kit	LHC0001	LHC0001M
Cytokine Human 25-Plex Panel	25	Eotaxin, GM-CSF, IFN-α, IFN-γ, IL-1β, IL-1RA, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p40/p70), IL-13, IL-15, IL-17, IP-10, MCP-1, MIG, MIP-1α, MIP-1β, RANTES, TNF-α + Buffer kit	LHC0009	LHC0009M
Cytokine Human 30-Plex Panel	30	EGF, Eotaxin, FGF-basic, G-CSF, GM-CSF, HGF, IFN-α, IFN-γ, IL-1β, IL-1RA, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p40/p70) IL-13, IL-15, IL-17, IP-10, MCP-1, MIG, MIP-1α, MIP-1β, RANTES, TNF-α, VEGF + Buffer kit	LHC6003	LHC6003M
Cytokine I Mouse Magnetic 4-Plex Panel	4	GM-CSF, IL-1β, IL-6, TNF-α + Buffer kit		LMC0003M
Cytokine II Human 5-Plex Panel	5	IFN-α, IL-12 (p40/p70), IL-13, IL-15, IL-17 + Buffer kit	LHC0007
Cytokine Monkey Magnetic 28 Plex Panel	28	EGF, Eotaxin, FGF-basic, G-CSF, GM-CSF, HGF, IFN-γ, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-15, IL-17, I-TAC, MCP-1, MDC, MIF, MIG, MIP-1α, MIP-1β, RANTES, TNF-α, and VEGF		LPC0003M
Cytokine Mouse 10-Plex Panel	10	GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p40/p70), TNF-α + Buffer kit	LMC0001	LMC0001M
Cytokine Mouse 20-Plex Panel	20	FGF basic, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, IL-12 (p40/p70), IL-17, IP-10, KC, MCP-1, MIG, MIP-1α, TNF-α, VEGF + Buffer kit	LMC0006	LMC0006M
Cytokine Rat 10-Plex Panel	10	GM-CSF, IL-1α, IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12 (p40/p70), TNF-α + Buffer kit	LRC0002	LRC0002M
Cytokine Ultrasensitive Human 10-Plex Panel	10	GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, TNF-α + Buffer kit	LHC6004	LHC6004M
Growth Factor Human 4-Plex Panel	4	EGF, FGF basic, G-CSF, VEGF + Buffer kit	LHC0004
Human Chemokine II 5-Plex Panel	5	ENA-78, I-309/CCL1, MDC/CCL22, MIP-3α/CCL20, TARC/CCL17	LHC0012
Inflammatory Cytokine Human 5-Plex Panel	5	GM-CSF, IL-1β, IL-6, IL-8, TNF-α + Buffer kit	LHC0003	LHC0003M
Inflammatory Cytokine Mouse 4-Plex Panel	4	GM-CSF, IL-1β, IL-6, TNF-α + Buffer kit	LMC0003
Th1/Th2 Cytokine Human 5-Plex Panel	5	IFN-γ, IL-2, IL-4, IL-5, IL-10 + Buffer kit	LHC0002
Th1/Th2 Cytokine Monkey 5-Plex Panel	5	IFN-γ, IL-2, IL-4, IL-10, TNF-α + Buffer kit	LPC0001
Th1/Th2 Cytokine Mouse 6-Plex Panel	6	IFN-γ, IL-2, IL-4, IL-5, IL-10, IL-12 (p40/70) + Buffer kit	LMC0002

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*This promotion is open only to customers in the US and Canada. Discount will apply to orders received by Life Technologies no later than July 31, 2013, or until promotional supplies are depleted, whichever comes first. Customer can use the discount only once. Discount only applies to a maximum of 1 kit per customer. Discount applies to the list price in effect at the time the order is received by Life Technologies. Cannot be combined with other discounts or promotions. Offer void where prohibited, licensed, or restricted by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.

*This promotion is open only to customers in Austria, Belgium, Czech Republic, Denmark, Finland, France, Hungary, Italy, Germany, Luxembourg, Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Switzerland, and the United Kingdom. Discount will apply to qualifying orders received by Life Technologies no later than July 31, 2013, or until promotional supplies are depleted, whichever comes first. Customer can use the discount only once. Discount only applies to a maximum of 1 kit per customer. Discount applies to the list price in effect at the time the order is received by Life Technologies. Cannot be combined with other discounts or promotions. Offer void where prohibited, licensed, or restricted by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.

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