High Content Screening (HCS)
 | Understanding Biology, Enabling Decisions.Advances in software, automation and hardware have now allowed imaging to expand into higher throughput applications often referred to as high content screening (HCS) or automated imaging. While many of our products can be translated for these applications there are special considerations and needs for HCS that require particular attention. Drawing on our decades of experience in fluorescence, Life Technologies offers Molecular Probes® validated tools and assays specifically for HCS platforms. Our products for automated imaging are:
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HCS New and Featured Products
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HCS Cell Health and Cytotoxicity Assays
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Webinar: Novel High Content Imaging Tools and Cell Health Assays
 | Original Air Date: April 3, 2012 In this free webinar, we will provide an overview on novel reagent options for high-content imaging from Molecular Probes®. We will also review the tools and technology platforms and focus most attention on the how to choose among the available tools that address multiparametric needs for cell health assays including:
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HCS Tools
 | High content screening is still an emerging technology and building and validating your own assays is often the best way to get the results you need. From antibodies to expression tags, Life Technologies offers a wide selection of reagents and tools for high content screening applications.
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Posters Presented at Scientific Meetings
- ThiolTracker™ Violet dye, a new 405 nm excitable fluorescent probe for detecting intracellular thiols in imaging-based assays
- A new approach for the detection of intracellular glutathione by fluorescence microscopy and flow cytometry
- Quantum dot (Qdot) labeling of gene expression in fresh frozen brain tissue using
high-throughput in situ hybridization
- Quantitative Analysis of Genotoxicity and Cytotoxicity to DNA Damaging Agents Using High-Content Imaging
- New fluorescent reagents for imaging based assays for the analysis of drug induced perturbations of cellular lipid metabolism
- LipidTOX™ Dyes for Adipocyte Staining in Routine Imaging Applications
- A non-radioactive method for detecting nascent protein synthesis by high-content imaging utilizing click chemistry
- Montioring mitotic cells and DNA content by automated imaging and analysis
- Click chemistry based detection of S-phase adherent cells using automated microscopy and image analysis
- High content analysis of cytotoxicity by laser scanning fluorescence Microplate cytometry
- Novel Click-iT® TUNEL assay for the detection of cell death
- High content imaging of endocytosis and phagocytosis using pHrodo™ conjugates
- Living Molecular Probes for the next generation
- BacMam gene delivery of targeted fluorescent proteins, Organelle Lights™ for HCS
- FluxOR™, a universal potassium channel assay
- Cell Cycle Analysis using Microplate Cytometry: A Comparison of Laser and Dye Combinations
- Utility of 405 nm excitable dyes in High Content Screening using an Acumen Explorer Microplate Cytometer
- High Throughput High Content Screening using a Multiple Laser Acumen® X3 Microplate Cytometer
- Multicolor Detection of CD45 on human monocytes with Quantum Dots in a high throughput format
