Imaging Apoptosis

Many different approaches are used in the study of programmed cell death, or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach for accurate assessment. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery. Life Technologies offers a wide array of apoptosis assays for measuring multiple components on a choice of assay platforms:

• Caspase activity assays
• DNA fragmentation and morphology
• Annexin V staining
• Membrane potential and other mitochondrial assays

• Also see flow cytometry assays for apoptosis