Apoptosis
 | Apoptosis (programmed cell death) is the genetically controlled ablation of cells during normal development. As with cell viability, no single parameter fully defines cell death in all systems; therefore, it is often advantageous to use several different approaches when studying apoptosis. Several methods have been developed to distinguish live cells from early and late apoptotic cells and from necrotic cells. |
Quick Links
Annexin V Translocation
 | Invitrogen offers highly fluorescent annexin V conjugates that provide quick and reliable detection methods for studying the externalization of phosphatidylserine, an indicator of intermediate stages of apoptosis. These conjugates are available as stand alone reagents or in kits designed to measure multiple parameters of apoptosis. | Products |
Membrane Permeability
 | Later stages of apoptosis are accompanied by an increase in membrane permeability, which allows some normally cell impermeant nucleic acid stains to cross the cell's membrane. Combinations of cell permeant and cell impermeant stains have been extensively used of the stages of apoptosis and cell-cycle distribution. | Products |
Mitochondria
 | The mitochondria plays an important role in the process of apoptosis. We offer a wide range of reagents and kits to quantitate its function including mitochondrial selective dyes and stains, antibodies, ELISAs and a lot more.
| Products |
Free Radical Detection
 | Find products for detection and quantitation of reactive oxygen species, nitric oxide and glutathione, including the new MitoSox™ Red mitochondrial superoxide indicator. | Products |
Caspase Activation
 | Products for caspase activation from Invitrogen include fluorimetric and colorimetric substrates and kits for multiple platforms as well as antibodies and ELISAs. | Products |
DNA Fragmentation
 | Invitrogen has a wide selection of reagents and kits for detecting the apoptotic breakdown of the nucleus resulting in collapse and fragmentation of the chromatin, degradation of the nuclear envelope and nuclear blebbing. | Products |
