Cell Viability, Proliferation & Function

Cell Viability, Proliferation & Function

Invitrogen offers a diverse selection of assays and antibodies for the analysis of apoptosis, cell cycle and DNA repair, cell viability and vitality, proliferation, migration, adhesion, chemotaxis, endo- and exocytosis, and angiogenesis. Many of the assays are fluorescence- or colorimetric-based, offering sensitivity, convenience as well as safety. These products have been validated on mutliple instrument platforms including microscopy, flow cytometry, microplate reader, or high content screening.

 

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Cell Health Assays

Learn More about Cell Health Assays

Apoptosis

Apoptosis 

An extensive portfolio of assays and antibodies for characterizing programmed cell death  including determining which cells are apoptotic, live and necrotic.  These products can also be used to identify  specific apoptotic stages (early, middle and late) through measurement of  parameters that include autophagy, cell membrane permeability,  mitochondrial dysfunction, caspase activation, and many more.

 

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Autophagy

Autophagy 

Cells use autophagy to digest damaged or defective molecules, effectively eliminating the stressors like mis-folded proteins and damaged organelles that can threaten cell health, or in the case of hypoxia and serum starvation, devour existing proteins and organelles to generate key nutrients for survival. It is also closely associated with apoptosis.

 

 

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Cell Viability & Cytotoxicity

Cell Viability & Cytotoxicity 

Invitrogen offers complete solutions for easy, sensitive determination of cell viability, cell vitality and  compound cytotoxicity.  These fluorescence-based and colorimetric-based products include PrestoBlue™ Cell Viability Reagent and LIVE/DEAD® assays as well as CellSensor™ lines for specific toxic responsive elements and more. 

 

 

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Cell Cycle

Cell Cycle 

Tools and kits to analyze cellular DNA content, regulation and modification of cell cycle related proteins, cell cycle checkpoint and DNA damage pathway analysis can be found in this section.  Products and platforms include antibodies, tools for flow cytometry, cell dyes and stains, and cell cycle analysis kits.

 

 

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Cell Proliferation

Cell Proliferation 

A wide selection of validated products to stimulate and measure cell proliferation,  for tracking DNA content or DNA synthesis including the new Click-iT® EdU proliferation kits. Other products include antibodies, media, and highly-potent growth factors.

 

 

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DNA Replication & Repair

DNA Replication & Repair 

Invitrogen has the tools you need to investigate cell processes involving DNA replication and repair including enzymes, nucleotides, antibodies, and assay kits.

 

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Ionic Homeostasis & Signaling

Ionic Homeostasis and Signaling Invitrogen offers a wide range of Molecular Probes® fluorescent dyes and probes for measuring ionic homeostasis including indicators for calcium, magnesium sodium, potassium, heavy metals and phosphates.  

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Nitro-Oxidative Stress

Nitro-Oxidative Stress Find products for detection and quantitation of reactive oxygen species, nitric oxide and glutathione, including the new MitoSox™ Red mitochondrial superoxide indicator. 

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Cell Metabolism

Cell Metabolism 

Invitrogen has a diverse array of platforms and products for studying cell function and drug, protein, and phosphate metabolic processes. These products include ion sensors, free radical generators and detectors.

 

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Cell Adhesion

Cell Adhesion 

Regulated adhesion of cells to substrates and tissues is critical in development and many disease processes.  Products found here can easily label cells and thus help determine the number, shape and, in many cases, the vitality of cells attached to matrix proteins or cells.  In addition products that monitor matrix protein degrading enzymes are included along with antibodies to critical proteins in the adhesion cascade.

 

 

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Chemotaxis & Cell Migration

Chemotaxis & Cell Migration 

Cell movement that occurs during processes like angiogenesis, metastasis or lymphocyte extravastion can be studied using fluorescent cell stains, recombinant cytokines that regulate these functions and antibodies to target proteins critical to these processes.

 

 

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Endocytosis, Exocytosis & Phagocytosis

Endocytosis and Phagocytosis 

We offer a wide range of products for understanding the processes of endocytosis, exocytosis, and phagocytosis. These include the new pH- sensitive pHrodo™ dyes and conjugates, fluorescently labeled bioparticles, ligands and tracers as well as fluorescent microspheres.

 

 

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Angiogenesis

Angiogenesis 

Invitrogen offers antibodies, proteins, and assay kits for the study of blood vessel growth through the processes of angiogenesis and vasculogenesis.

 

 

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