Media Optimization and Process Development Services

Let our expertise and innovation work for you. Gibco PD-Direct® Bioprocess Services offers media development programs tailored to meet the specific requirements of your process needs.  We offer three major program options that can be further customized or used in combination to enhance performance of your cell line:

  • Traditional program – conventional small scale vessels used for development work
  • Consult program – designed for customers that are unable to transfer their cell line for external studies but wish to leverage Gibco® PD-Direct® Bioprocess Services' experience in media development
  • SimCell™ program - high throughput microbioreactor technology allowing for exploration of a larger DOE space (link this to new high throughput SimCell page

Our process development team can help you find a media solution that fits your needs. We have a proven track record of successfully developing cell line specific and platform media for our customers globally. Our approach includes:

  • Consultation with our team to define your process needs and options
  • Scope definition for development of a shared work plan with defined goals, milestones, and deliverables
  • Design of Experiments (DOE) to optimize concentrations of media components to identify suitable base and feed media formulations
  • Combination of media and process conditions (pH, dissolved oxygen, temperature, etc.)
  • Scalability evaluation of media in bench top bioreactors leading to seamless transfer to the partner’s team for validation


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