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Gene-Related Products
Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP
Citations & References
- Authors: Ohnishi, K; Nagata, Y; Takahashi, A; Taniguchi, S; Ohnishi, T
- Journal: ONCOLOGY REPORTS 2008 1:57-61
- Product Usage: Silencer® siRNAs
- ID: PN82441
1448c8ad46bb09c4bed7cb43e35e15a6_Citations
Gene expression profile in colon cancer cells with respect to XIAP expression status
Citations & References
- Authors: Qiao, L; Li, GHY; Dai, Y; Wang, JD; Li, ZS; Zou, B; Gu, Q; Ma, J; Pang, R; Lan, HY; Wong, BCY
- Journal: INTERNATIONAL JOURNAL OF COLORECTAL DISEASE 2009 3:245-260
- Product Usage: 7900HT Fast Real-Time PCR System;SYBR® Green Reagents
- ID: PN114105
b65eac96a2e7ed6afc6b462e93dba99e_Citations
Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma
Citations & References
- Authors: Krepela, E; Dankova, P; Moravcikova, E; Krepelova, A; Prochazka, J; Cermak, J; Schuetzner, J; Zatloukal, P; Benkova, K
- Journal: INTERNATIONAL JOURNAL OF ONCOLOGY 2009 6:1449-1462
- Product Usage: Capillary Electrophoresis Systems;TaqMan® RT-PCR (One-Step & Two-Step) Kits & Reagents
- ID: PN111285
79e80f5203ab34b599d1565ab6375cb7_Citations
Molecular targeting of Bcl-2 overcomes prostate cancer cell adaptation to XIAP gene downregulation
Citations & References
- Authors: Nakano, Y; Bilim, V; Yuuki, K; Muto, A; Kato, T; Nagaoka, A; Tomita, Y
- Journal: Prostate Cancer and Prostatic Diseases 2009 1:34-40
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN119241
20ae66585f50ef995c877537dcef4f3c_Citations
ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis.
Citations & References
- Authors: Sanna MG, da Silva Correia J, Luo Y, Chuang B, Paulson LM, Nguyen B, Deveraux QL, Ulevitch RJ.
- Journal: J Biol Chem (2002) 277:30454-30516
- Product Usage: Human embryonic kidney cells (293T) were grown in DMEM with 10% FBS, and were transfected 18 h later using LipofectAMINE Plus reagent for 3 h and incubated for 18 h before lysis. MCF7-Fas cells were grown in RPMI 1640 containing 10% fetal bovine serum, 200 µg/ml G418, and 100 µg/ml hygromycin and 24 h after plating were transfected using LipofectAMINE Plus reagent 24 h after transfection, cells were treated with anti-Fas antibody (150 ng/ml). After 16 h, cells were fixed and stained.
- ID: PN62834
266710f17eae1ddcdbd353dc54f49f01_Citations
Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
Citations & References
- Authors: Gill, C; Dowling, C; O'Neill, AJ; Watson, RWG
- Journal:
- Product Usage: Silencer® siRNAs;TaqMan® Gene Expression Assays
- ID: PN105100
64992c253be5ac0c6ad94772d0e4d02a_Citations
Structural basis for the inhibition of caspase-3 by XIAP.
Citations & References
- Authors: Riedl SJ, Renatus M, Schwarzenbacher R, Zhou Q, Sun C, Fesik SW, Liddington RC, Salvesen GS
- Journal: Cell (2001) 104:791-800
- Product Usage:
- ID: PN44823
- Catalog #s
- A22121
3c4dbca5fa732d03efb4b0a88a837b29_Citations
Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.
Citations & References
- Authors: MacFarlane M, Merrison W, Bratton SB, Cohen GM
- Journal: J Biol Chem (2002) 277:36611-36616
- Product Usage:
- ID: PN48549
b36386583d6f2df72b8fc8dca09e34a4_Citations
Inhibitor of apoptosis protein (IAP) profiling in experimental autoimmune encephalomyelitis (EAE) implicates increased XIAP in T lymphocytes.
Citations & References
- Authors: Moore CS, Hebb AL, Robertson GS,
- Journal: J Neuroimmunol (2008) 193:94-105
- Product Usage: Visualization of demyelinated lesions in mouse spinal cord cryostat sections.
- ID: PN67285
b15efe6a95ccb9124597a04c597376f5_Citations
Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis.
Citations & References
- Authors: Silke J, Kratina T, Ekert PG, Pakusch M, Vaux DL,
- Journal: J Biol Chem (2004) 279:4313-4321
- Product Usage: Tagged XIAP and Grim, and paracaspase inserts were removed from pEF C-terminal FLAG-tagged vectors with BamHI NotI and cloned into pcDNA5 FRT TO digested with BamHI NotI. Stable cell lines were established by transiently transfecting the Flp-In T-REx 293 cell line with pcDNA5 FRT TO constructs with the recommended amount of pOG44. 24 h after transfection cells were split into 15 cm tissue culture plates and selected with 1.6 µg/ml hygromycin.
- ID: PN64577
b0a665a28efd91535abb111d656ecd04_Citations
Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1.
Citations & References
- Authors: Hofer-Warbinek R, Schmid JA, Stehlik C, Binder BR, Lipp J, de Martin R
- Journal: J Biol Chem (2000) 275:22064-22068
- Product Usage:
- ID: PN59206
b0f7ec2784174fdce2f2de20d3941d96_Citations
Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-kappaB-independent, proteasome-mediated mechanism.
Citations & References
- Authors: Golovine K, Makhov P, Uzzo RG, Kutikov A, Kaplan DJ, Fox E, Kolenko VM
- Journal:
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN120610
3aa7b86ccbbe73dcde26cac48a0ca163_Citations
Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.
Citations & References
- Authors: Zou H, Yang R, Hao J, Wang J, Sun C, Fesik SW, Wu JC, Tomaselli KJ, Armstrong RC
- Journal: J Biol Chem (2003) 278:8091-8098
- Product Usage:
- ID: PN51284
fb2e636577105f243646d6f1e199f0ba_Citations
A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection.
Citations & References
- Authors: Holcik M, Lefebvre C, Yeh C, Chow T, Korneluk RG
- Journal: Nature Cell Biology (1999) 1:190-192
- Product Usage: The authors constructed a bicistronic vector by cloning the B-galactosidase and CAT genes into pcDNA3. Insertion of a 5' UTR from human or mouse x-linked inhibitor-of-apoptosis (XIAP) directed translation of the second cistron, indicating the presence of an internal ribosome-entry site (IRES). Transient transfection and expression were done in NIH-3T3, HeLa, HEL299, 293, SH-Sy5y, H460, H520, H661, and SKOV3 cells. Cells were collected in PBS after 48 hours and extractes were prepared by freeze-t
- ID: PN65173
- Catalog #s
- V79020
7e51dc91e1459243933b9ac53a8c953f_Citations
