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Gene-Related Products
Hamartin Mouse Monoclonal Antibody (clone 5C8A12) View 4 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 370400 | 100 µg | 299.00 |
Description
Mouse anti-Hamartin; Unconjugated Monoclonal antibody specific to Human Hamartin. This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-Hamartin recognizes View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Immunoprecipitation
ELISA
Western Blot
- Host
-
Mouse
- Clonality
-
Monoclonal
- Clone ID
-
5C8A12
- Target Gene
-
Hamartin
- Gene ID
-
7248
- Label or Dye
-
Unconjugated
- Purification
-
Affinity Purified
- Product Size
-
100 µg
- Shipping Condition
-
Wet Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this product370400
c2c1b68eb248cba1b696840857e54051_CmgtBuyProduct
Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms.
Citations & References
- Authors: Pymar LS, Platt FM, Askham JM, Morrison EE, Knowles MA
- Journal: Hum Mol Genet 2008 13:2006-2017
- Product Usage: siPORT™ Transfection Agents
- ID: PN120685
938953bb8a9fb4ef839b4f4e69a3b35d_Citations
Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms
Citations & References
- Authors: Pymar, LS; Platt, FM; Askham, JM; Morrison, EE; Knowles, MA
- Journal: HUMAN MOLECULAR GENETICS 2008 13:2006-2017
- Product Usage: Capillary Electrophoresis Systems;SYBR® Green Reagents
- ID: PN81852
a4523fede85359d061e278662da5e1b5_Citations
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells.
Citations & References
- Authors: Kwiatkowski DJ; Zhang H; Bandura JL; Heiberger KM; Glogauer M; el-Hashemite N; Onda H
- Journal: Human Molecular Genetics 2002 5:525-534
- Product Usage: AmpliTaq Gold® Reagents
- ID: PN89234
47b039f251990bd8271bbb18a2c02491_Citations
TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Citations & References
- Authors: Dibble CC, Elis W, Menon S, Qin W, Klekota J, Asara JM, Finan PM, Kwiatkowski DJ, Murphy LO, Manning BD,
- Journal: Mol Cell (2012) 47:535-546
- Product Usage: Immunoprecipitation from fractions collected from sucrose density gradients
- ID: PN131924
- Catalog #s
- 370400
6ec372426210cefa80f2db4eccc78220_Citations
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.
Citations & References
- Authors: Lamb RF, Roy C, Diefenbach TJ, Vinters HV, Johnson MW, Jay DG, Hall A
- Journal: Nat Cell Biol (2000) 2:281-287
- Product Usage:
- ID: PN37117
1879d84e181b6262704e95372dc9f4dc_Citations
A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles
Citations & References
- Authors: Pollizzi, K; Malinowska-Kolodziej, I; Doughty, C; Betz, C; Ma, J; Goto, J; Kwiatkowski, DJ
- Journal: HUMAN MOLECULAR GENETICS 2009 13:2378-2387
- Product Usage: SYBR® Green Reagents
- ID: PN103286
71e11fa9c2ea505a75bc330c73145f81_Citations
Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin.
Citations & References
- Authors: Hodges A K; Li S; Maynard J; Parry L; Braverman R; Cheadle J P; DeClue J E; Sampson J R;
- Journal: Hum Mol Genet (2001) 10:2899-3804
- Product Usage: Transient transfection of COS-7 cells with plasmid DNA for protein expression, using Lipofectamine 2000 reagent.
- ID: PN65026
- Catalog #s
- 11668019
5d5bbd55157f38a19f155390f2dc7430_Citations
Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas.
Citations & References
- Authors: Weber RG; Hoischen A; Ehrler M; Zipper P; Kaulich K; Blaschke B; Becker AJ; Weber-Mangal S; Jauch A; Radlwimmer B; Schramm J; Wiestler OD; Lichter P; Reifenberger G
- Journal:
- Product Usage: Capillary Electrophoresis Systems
- ID: PN70546
1469c5763b513b6bcf582f59effa8f26_Citations
Additional Document: Hum. Mol. Genet. 2005-05
Product Literature
- Download
- Version: 20 June 2007
f0bda020d2470f2e74990a07a607ebd9_Brochures
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Manual / Product Insert
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TaqMan® OpenArray® Hu Signal Transduction Panel Content
Product Literature
- Download
- Version: 12 November 2012
c5d9256689c43036581f781c61f26e50_Brochures
TaqMan® OpenArray® Human Signal Transduction Panel, QuantStudio™ 12K Flex Content
Product Literature
- Download
- Version: 12 November 2012
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