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Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-alpha Signaling.
Citations & References
- Authors: Xia Pu; Wang Lijun; Moretti Paul A B; Albanese Nathaniel; Chai Fugui; Pitson Stuart M; D'Andrea Richard J; Gamble Jennifer R; Vadas Mathew A;
- Journal: J Biol Chem (2002) 277:7996-8003
- Product Usage: LipofectAMINE 2000 was used for transient transfections of HEK 293T cells.
- ID: PN63725
- Catalog #s
- 11668027
TRAF2 Suppresses Basal IKK Activity in Resting Cells and TNFα Can Activate IKK in TRAF2 and TRAF5 Double Knockout Cells
Citations & References
- Authors: Zhang, LQ; Blackwell, K; Thomas, GS; Sun, SJ; Yeh, WC; Habelhah, H
- Journal: JOURNAL OF MOLECULAR BIOLOGY 2009 3:495-510
- Product Usage: SYBR® Green Reagents
- ID: PN104478
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2.
Citations & References
- Authors: Li Xiaoming; Yang Yili; Ashwell Jonathan D;
- Journal: Nature (2002) 416:345-352
- Product Usage: The pCMVSPORT-Bgal reporter plasmid was purchased. 293 cells and HeLa cells were grown in DMEM containing 10% heat-inactivated fetal calf serum, antibiotics, 4 mM glutamine, and 5 10-5 M B-mercaptoethanol. Jurkat and 4E3 cells were cultured in RPMI-1640 supplemented as above. Cells were transfected with the indicated expression vectors using Lipofectamine 2000.
- ID: PN63625
Traf2 interacts with Smad4 and regulates BMP signaling pathway in MC3T3-E1 osteoblasts
Citations & References
- Authors: Shimada, K; Ikeda, K; Ito, K
- Journal: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2009 3:775-779
- Product Usage: TaqMan® Master Mixes
- ID: PN112473
CD30 induction of human immunodeficiency virus gene transcription is mediated by TRAF2.
Citations & References
- Authors: Tsitsikov EN, Wright DA, Geha RS
- Journal: Proc Natl Acad Sci U S A (1997) 94:1390-1395
- Product Usage: cDNAs for truncated and full length TRAF1 and TRAF2 proteins were obtained by PCR amplification using Pfu polymerase. This was followed by incubation with Taq to allow for the addition of single 3'A overhangs to enable direct direct cloning into the pCRII vector. For expression experiments, DNA fragments were cloned into pcDNA3. Expression constructs were transfected into KT-3 cells. (Note: Current version of pcDNA3 is pcDNA3.1 +/-.)
- ID: PN60343
cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand.
Citations & References
- Authors: Dupoux A, Cartier J, Cathelin S, Filomenko R, Solary E, Dubrez-Daloz L,
- Journal: Blood (2009) 113:175-185
- Product Usage: Assaying extracts of cultured human monocytes
- ID: PN68304
EBV LMP2A affects LMP1-mediated NF-κB signaling and survival of lymphoma cells by regulating TRAF2 expression
Citations & References
- Authors: Guasparri, L; Bubman, D; Cesarman, E
- Journal: BLOOD 2008 7:3813-3820
- Product Usage: SYBR® Green Reagents
- ID: PN78014
The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.
Citations & References
- Authors: Heyninck K, De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G, Beyaert R
- Journal: J Cell Biol (1999) 145:1471-1482
- Product Usage:
- ID: PN34257
CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1.
Citations & References
- Authors: Mann J, Oakley F, Johnson PW, Mann DA,
- Journal: J Biol Chem (2002) 277:17125-17138
- Product Usage: Cells were cultured in RPMI-1640 supplemented with 100 units/ml penicillin, 100 µg/ml streptomycin, 2 mM L-glutamine, and 10% fetal calf serum. Transient induction of IL-6 mRNA by anti-CD40 treatment was associated with reduced p50:p65 NF-B DNA binding and elevated binding of CBF1 to a site overlapping the NF-B site. The authors found that prolonged induction of CBF1 may contribute to the transient nature of the IL-6 response.
- ID: PN63519
Array Plate: Human TNFR2 Pathway (XLS)
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Array Plate: Human Toll Pathway Core Components (XLS)
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Array Plate: Human TNFR1 Pathway (XLS)
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Array Plate: Human Apoptotic Pathways Triggered by HIV1 (XLS)
Manual / Product Insert