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CellSensor® NFkB-bla RAW 264.7 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1673 | 1 vial | 9949.00 |
Description
The CellSensor® NFκB-bla RAW264.7 mouse macrophage cell line contains a beta-lactamase reporter gene under control of a stably integrated NFκB response element. View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
Rabbit anti-TLR7 (C-term)
Manual / Product Insert
Type I IFN receptor and the B cell antigen receptor regulate TLR7 responses via distinct molecular mechanisms.
Citations & References
- Authors: Poovassery JS, Bishop GA,
- Journal: J Immunol (2012) 189:1757-1764
- Product Usage: Western blotting of lysates made from mouse splenic B cells
- ID: PN132023
- Catalog #s
- 44621G
Comparison of human B cell activation by TLR7 and TLR9 agonists
Citations & References
- Authors: Hanten, JA; Vasilakos, JP; Riter, CL; Neys, L; Lipson, KE; Alkan, SS; Birmachu, W
- Journal:
- Product Usage: 7900HT Fast Real-Time PCR System;TaqMan® Gene Expression Assays
- ID: PN84153
Comparison of human B cell activation by TLR7 and TLR9 agonists.
Citations & References
- Authors: Hanten JA; Vasilakos JP; Riter CL; Neys L; Lipson KE; Alkan SS; Birmachu W
- Journal:
- Product Usage: TaqMan® Arrays
- ID: PN96795
Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.
Citations & References
- Authors: Du M, Butchi NB, Woods T, Peterson KE
- Journal: PLoS One (2011) 6:e22454-e22454
- Product Usage: Assaying culture supernatants from mouse brain primary astrocytes
- ID: PN129645
- Catalog #s
- LMC0006
Signaling through TLR7 enhances the immunosuppressive activity of murine CD4+CD25+ T regulatory cells.
Citations & References
- Authors: Forward NA, Furlong SJ, Yang Y, Lin TJ, Hoskin DW
- Journal: J Leukoc Biol 2010 1:117-125
- Product Usage: TaqMan® Master Mixes
- ID: PN124547
TLR7 ligands induce higher IFN-alpha production in females.
Citations & References
- Authors: Berghofer B, Frommer T, Haley G, Fink L, Bein G, Hackstein H
- Journal: J Immunol 2006 4:2088-2096
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN127902
Reciprocal regulation of activating and inhibitory Fc{gamma} receptors by TLR7/8 activation: implications for tumor immunotherapy.
Citations & References
- Authors: Butchar JP, Mehta P, Justiniano SE, Guenterberg KD, Kondadasula SV, Mo X, Chemudupati M, Kanneganti TD, Amer A, Muthusamy N, Jarjoura D, Marsh CB, Carson WE 3rd, Byrd JC, Tridandapani S
- Journal: Clin Cancer Res 2010 7:2065-2075
- Product Usage: StepOnePlus™ Real-Time PCR System
- ID: PN123751
- Catalog #s
- 4376598
- 4376599
- 4376600
- ZGEXSCSTEPONEP
- ZGEXSCSTEPONEP3Y
Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.
Citations & References
- Authors: Butchi NB, Pourciau S, Du M, Morgan TW, Peterson KE
- Journal: J Immunol (2008) 180:7604-7612
- Product Usage: Assaying mouse brain extracts
- ID: PN129591
- Catalog #s
- LMC0006
Human dendritic cells stimulated via TLR7 and/or TLR8 induce the sequential production of Il-10, IFN-gamma, and IL-17A by naive CD4+ T cells.
Citations & References
- Authors: Lombardi V, Van Overtvelt L, Horiot S, Moingeon P
- Journal: J Immunol 2009 6:3372-3379
- Product Usage: Silencer® Select siRNAs;7300 Real-Time PCR System;TaqMan® Gene Expression Assays
- ID: PN76854
- Catalog #s
- 111
- 4330087R
- 4331182
- 4350814
- 4351101
- 4351101R
- 4351103
- 4351103R
- 4351368
- 4351370
- 4351372
- 4359284
- 4359286
- 4363914
- 4363915
- 4367246
- 4379633
- 4379635
- 4390771
- 4390815
- 4390816
- 4390817
- 4390818
- 4390821
- 4390822
- 4390824
- 4390825
- 4390826
- 4392420
- 4392421
- 4392422
- 4404011
- 4404012
- 4404014
- 4407268
- 4407269
- 4407270
- 4427030
- 4427031
- 4427032
- 4427033
- 4427034
- 4427035
- 4427036
- 4427037
- 4427038
- 4427039
- 4444198
- 4444246
- 4444247
- 4444260
- ABsiRNA3
- ABsiRNA4
- ABsiRNA5
- ABsiRNA6
- ZGEXSC7300
- ZGEXSC73003Y
Human Dendritic Cells Stimulated via TLR7 and/or TLR8 Induce the Sequential Production of Il-10, IFN-γ, and IL-17A by Naive CD4(+) T Cells
Citations & References
- Authors: Lombardi, V; Van Overtvelt, L; Horiot, S; Moingeon, P
- Journal: JOURNAL OF IMMUNOLOGY 2009 6:3372-3379
- Product Usage: Silencer® siRNAs;TaqMan® Gene Expression Assays
- ID: PN99942
Investigation of TLR5 and TLR7 as candidate genes for susceptibility to systemic lupus erythematosus
Citations & References
- Authors: Sanchez, E; Callejas-Rubio, JL; Sabio, JM; Gonzalez-Gay, MA; Jimenez-Alonso, J; Mico, L; de Ramon, E; Camps, M; Suarez, A; Gutierrez, C; Garcia-Portales, R; Tolosa, C; Ortego-Centeno, N; Sanchez-Roman, J; Garcia-Hernandez, FJ; Gonzalez-Escribano, MF; Mart
- Journal: Clinical and Experimental Rheumatology 2009 2:267-271
- Product Usage: TaqMan® SNP Genotyping Assays
- ID: PN102590
Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders
Citations & References
- Authors: Moller-Larsen, S; Nyegaard, M; Haagerup, A; Vestbo, J; Kruse, TA; Borglum, AD
- Journal: THORAX 2008 12:1064-1069
- Product Usage: Capillary Electrophoresis Systems
- ID: PN115383