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TBK1 Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4070 | 1 mg | 5400.00 |
Description
TBK1 is similar to the IKB kinases and is involved with NF-kappa B activation. In addition, TBK1, along with IKK epsilon, is involved with IRF3 signaling. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
TBK1, NAK
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
1 mg
- Accession Number
-
NP_037386
- Molecular Weight
-
87.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productTBK1 Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR5618B | 100 µg | 1250.00 |
Description
TBK1 is similar to the IKB kinases and is involved with NF-kappa B activation. In addition, TBK1, along with IKK epsilon, is involved with IRF3 signaling. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
TBK1, NAK
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
100 µg
- Accession Number
-
NP_037386
- Molecular Weight
-
87.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
TBK1 Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3504 | 10 µg | 376.00 |
Description
TBK1 is similar to the IKB kinases and is involved with NF-kappa B activation. In addition, TBK1, along with IKK epsilon, is involved with IRF3 signaling. View full product details >
General Specifications
- Gene ID
-
29110
- Species
-
Human
- Target Gene
-
TANK-binding kinase 1
- Gene Aliases
-
TBK1, NAK
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_037386
- Molecular Weight
-
87.7 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-pSer (PKC) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3560 | 25 µg | 3049.00 |
Description
A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.
For use in combination with the
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 5 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3178 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled serine⁄threonine peptide substrate which can be used for kinase screening in an antibody-free format. View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CSNK1G1, CSNK1G2, CSNK1G3, IKBKB, TBK1
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® ISRE-bla RA-1 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1674 | 1 vial | 9949.00 |
Description
The CellSensor® ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE). This cell line was View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
LanthaScreen® Tb-pSer (PKC) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3561 | 1 mg | 17050.00 |
Description
A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.
For use in combination with the
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-PKC Substrate
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3506 | 1 mg | 655.00 |
Description
A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.
For use in combination with the LanthaScreen™ Tb-pSer (PKC Substrate) antibody (PV3560)
View full product details >
General Specifications
- Substrate
-
Fluorescein-PKC
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1919 Da
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Amino Acid Sequence
-
Fluorescein- RFARKGSLRQKNV
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
TBK1 LanthaScreen Eu Binding Assay Validation Packet
Manual / Product Insert
TBK1 LanthaScreen Activity Assay Validation Packet
Manual / Product Insert
TBK1 Recombinant Human Protein
MSDS
TBK1 Recombinant Human Protein
MSDS
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
Citations & References
- Authors: Thurston, TLM; Ryzhakov, G; Bloor, S; von Muhlinen, N; Randow, F
- Journal: NATURE IMMUNOLOGY 2009 11:1215-U103
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN109946
Negative Regulation of Virus-triggered IFN-β Signaling Pathway by Alternative Splicing of TBK1
Citations & References
- Authors: Deng, WW; Shi, MD; Han, MF; Zhong, J; Li, ZH; Li, WN; Hu, Y; Yan, LC; Wang, J; He, Y; Tang, H; Deubel, V; Luo, XP; Ning, Q; Sun, B
- Journal: JOURNAL OF BIOLOGICAL CHEMISTRY 2008 51:35590-35597
- Product Usage: 7900HT Fast Real-Time PCR System
- ID: PN98017
