You searched for: STAT3 [564 matches]

Description

The STAT3 [pY705] ELISA research use only kit is designed to detect and quantify the level of STAT3 protein phosphorylated at tyrosine residue 705. This assay is intended for the   View full product details >

General Specifications

Marker

STAT3

Gene ID

6774

Species

Rat
Human
Mouse

Platform

Microplate Reader

Gene Symbol

STAT3

Sensitivity

<0.9 U⁄mL

Target Gene

signal transducer and activator of transcription 3 (acute-phase response factor)

Gene Aliases

APRF, FLJ20882, HIES, MGC16063

Label or Dye

HRP (Horseradish Peroxidase)

Product Size

96 tests

Concentration

1.6 U⁄ml

Sample Volume

10 µl

Protein Family

Transcription Factors

Incubation Time

4 hrs

Accession Number

NM_003150.3
NM_213662.1
NM_139276.2
NP_644805.1
NP_998827.1
NP_003141.2

Cross-Reactivity

Rat
Mouse

Detection Method

Colorimetric

Research Category

Signal Transduction

Sample Type (Specific)

Cell Extracts

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Drug Discovery & Development

User Ratings

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Description

STAT3 expressed as a fusion with GFP (Green Fluorescent Protein) to act as a physiological substrate for the Janus family of tyrosine kinases.

For use in combination with   View full product details >

General Specifications

Substrate

STAT3

Label or Dye

GFP (EmGFP)

Product Size

10 nmol

Target Enzyme

Tyrosine Kinases

Substrate Type

Kinase Substrate

Detection Method

Fluorescent

Molecular Weight

145200 Da

Validated Kinases

JAK1, JAK2, JAK3, TYK2

Substrate Properties

Protein-Based Substrate

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development

User Ratings

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Description

STAT3 [pY705] PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat STAT3 [pY705]. This antibody is validated for use in Western Blot, Flow Cytometry. Anti-STAT3 [   View full product details >

General Specifications

Reactivity

Rat
Mouse
Human

Validated Application

Western Blot

Host

Rabbit

Clonality

Polyclonal

Target Gene

STAT3 [pY705]

Gene ID

6774

Label or Dye

Unconjugated

Target Modification State

Phospho

Product Size

10 blots

Research Category

Signal Transduction

Purity or Quality Grade

Azide Free

Shipping Condition

Approved for shipment on Wet or Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

The JAK/STAT3 signaling pathway is known to be activated by cytokines such as IL-6. In this pathway, binding of IL-6 to its cell-surface receptors results in the activation of JAKs   View full product details >

General Specifications

System

LanthaScreen®

Readout

End Point

Reporter

GFP (EmGFP)

Cell State

Dividing Cells

Antagonists

IFN-alpha

Gene Symbol

STAT3

Product Size

1 vial

Primary Agonist

IL-6

Druggable Target

Cytokines
Kinases

Alternate Agonists

IL-6

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

This mouse anti-STAT3 monoclonal antibody is specific to human, mouse and rat STAT3. STAT3 monoclonal antibody recognizes the expressed product of the STAT3 gene also known as   View full product details >

General Specifications

Reactivity

Rat
Mouse
Human

Validated Application

Electrophoretic Mobility Shift Assay
Immunoprecipitation
Western Blot
Chromatin Immunoprecipitation
ELISA

Host

Mouse

Clonality

Monoclonal

Clone ID

ST3-5G7

Target Gene

STAT3

Gene ID

6774

Label or Dye

Unconjugated

Purification

Affinity Purified

Product Size

100 µg

Research Category

Signal Transduction

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis
• RNAi, Epigenetics & Non-Coding RNA Research

User Ratings

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Description

This rabbit anti-STAT3 [pS727] polyclonal antibody is specific to human, mouse and rat STAT3 [pS727]. STAT3 [pS727] polyclonal antibody recognizes the expressed product of the   View full product details >

General Specifications

Reactivity

Rat
Mouse
Human

Validated Application

Western Blot

Host

Rabbit

Clonality

Polyclonal

Target Gene

STAT3 [pS727]

Gene ID

6774

Label or Dye

Unconjugated

Target Modification State

Phospho

Product Size

10 blots

Research Category

Signal Transduction

Purity or Quality Grade

Azide Free

Shipping Condition

Approved for shipment on Wet or Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes Signal Transducer and Activator of Transcription (STAT3 [pY705]) in human samples.

  View full product details >

General Specifications

Reactivity

Human

Validated Application

Western Blot
ELISA

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Monoclonal

Clone ID

3H16L22

Antibody Fragment

Whole Antibody

Target Gene

Signal transducer and activator of transcription 3

Gene ID

6774

Gene Symbol

STAT3

Accession Number

P40763

Label or Dye

Unconjugated

Purification

Purified

Concentration

0.5 mg⁄ml

Form

Liquid

Neutralizing Antibody

No

Product Size

100 µg

Protein Family

Transcription Factors

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes STAT3 in human samples.

Antibody Specifications:

• Validated in Western Blot and

General Specifications

Reactivity

Human

Validated Application

ELISA
Western Blot

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Polyclonal

Clone ID

3HCLC

Antibody Fragment

Whole Antibody

Target Gene

STAT3

Gene ID

6774

Label or Dye

Unconjugated

Form

Liquid

Neutralizing Antibody

No

Product Size

100 µg

Comments

Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)

Shipping Condition

Approved for shipment on Wet or Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product

Description

Acetyl Stat3 (Lys685) rabbit polyclonal antibody recognizes human Acetyl Stat3 (Lys685) in western blot.

General Specifications

Reactivity

Human

Validated Application

Western Blot

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Polyclonal

Antibody Fragment

Whole Antibody

Target Gene

Acetyl Stat3

Gene ID

6774

Label or Dye

Unconjugated

Target Modification State

Acetylated

Form

Liquid

Neutralizing Antibody

No

Product Size

100 µl

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product

Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes Signal Transducers and Activators of Transcription 3 (STAT3 [pY705]) in human samples.

Antibody   View full product details >

General Specifications

Reactivity

Human

Validated Application

Western Blot
ELISA

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Polyclonal

Clone ID

3HCLC

Antibody Fragment

Whole Antibody

Target Gene

STAT3

Gene ID

6774

Accession Number

P40763

Label or Dye

Unconjugated

Concentration

0.5 mg⁄ml

Form

Liquid

Neutralizing Antibody

No

Product Size

100 µg

Protein Family

Transcription Factors

Comments

Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product

Description

A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.

For use in   View full product details >

General Specifications

Format

384-well plate

Readout

End Point

Technique

TR-FRET

Reactivity

Human

Label or Dye

GFP (EmGFP)
Terbium (Tb)

Product Size

1 mg

Target Enzyme

Tyrosine Kinases

Validated Kinases

JAK1, JAK2, JAK3, TYK2

Antibody Molecular Weight

150000 Da

Excitation⁄Emission (nm)

340⁄490, 520

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product

Description

A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.

For use in   View full product details >

General Specifications

Format

384-well plate

Readout

End Point

Technique

TR-FRET

Reactivity

Human

Label or Dye

GFP (EmGFP)
Terbium (Tb)

Product Size

25 µg

Target Enzyme

Tyrosine Kinases

Validated Kinases

JAK1, JAK2, JAK3, TYK2

Antibody Molecular Weight

150000 Da

Excitation⁄Emission (nm)

340⁄490, 520

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product