SMAD5 Mouse Monoclonal Antibody (clone ZS004)

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
395700 100 µg 299.00

Description

Ms anti-Smad5; Unconjugated Monoclonal antibody specific to Human, (Rat, Mouse) Smad5 . This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-Smad5   View full product details >

General Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
ZS004
Target Gene
Smad5
Gene ID
4090, 59328
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
100 µg
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis

User Ratings

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395700
3a9889abaca6bf7bdf08183200c87add_CmgtBuyProduct

SMAD1/5 [pS463/465] Monoclonal Antibody (clone 31H14L11), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
700047 100 µg 299.00

Description

This purified ABfinityâ„¢ recombinant rabbit anti-SMAD1/5 [pS463/465] monoclonal antibody is specific to human SMAD1/5 [pS463/465] and does not recognize non-phosphorylated   View full product details >

General Specifications

Reactivity
Human
Validated Application
Immunohistochemistry
Flow Cytometry
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
31H14L11
Antibody Fragment
Whole Antibody
Target Gene
Smad1/5 [pS463/pS465]
Gene ID
4086, 4090
Accession Number
Q15797, Q99717
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Confocal Microscope
Fluorescence Microscope
Flow Cytometer
Product Size
100 µg
Quantity
1
Volume
200 µl
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis

User Ratings

Ratings IconRate this product

700047
44e03a821ffc2c1ce0be5a9c046c727b_CmgtBuyProduct

Mouse anti-Smad5

Manual / Product Insert

Catalog #s
395700
8430b32b5bac908e765df8813d4405c5_Manuals

Rabbit anti-Smad5

Manual / Product Insert

Catalog #s
513700
3cfbdf468f0a03187f6cee51a25e5e9a_Manuals

SMAD5 Mouse Monoclonal Antibody (clone ZS004)

MSDS

MSDS Files
395700
Catalog #s
395700
bccb34022a7699a52b9573a2f41bb6ad_MSDS

SMAD5 VALIDATED STEALTH DUOPAK

MSDS

MSDS Files
461720
461721
468004
Catalog #s
451720
a13fdad45b9cc605e14825454e257109_MSDS

Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis.

Citations & References

  • Authors: Rai D, Kim SW, McKeller MR, Dahia PL, Aguiar RC
  • Journal: Proc Natl Acad Sci U S A 2010 7:3111-3116
  • Product Usage: TaqMan® MicroRNA Assays
  • ID: PN124676
Catalog #s
fdc0e53af172f94988a2b030dd6a39eb_Citations

Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.

Citations & References

  • Authors: Nagasako T; Sugiyama T; Mizushima T; Miura Y; Kato M; Asaka M
  • Journal: The Journal of Biological Chemistry 2002 7-Jun:4821-4825
  • Product Usage: Silencer® siRNAs
  • ID: PN72049
Catalog #s
174e35ed5a52c992994d7a58a661b9bd_Citations

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.

Citations & References

  • Authors: Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM
  • Journal: Mol Cell Biol 2008 1:248-257
  • Product Usage: TaqMan® Master Mixes
  • ID: PN121245
Catalog #s
eeefe3edff28b6a4dddba132bb5469c8_Citations

Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.

Citations & References

  • Authors: Nishimura R, Kato Y, Chen D, Harris SE, Mundy GR, Yoneda T
  • Journal: J Biol Chem (1998) 273:1872-1879
  • Product Usage: Relevan Smad family members involved in osteoblastic differentiation were isolated. Overexpression of point-mutated Smad5 or a C-terminal deletion mutatnt DPC4 in pcDNA3 blocked the induction of alkaline phosphatase activity, osteocalcin production, and Smad5-DPC4 signaling cascades upon BMP-2 treatment in C2C12 cells. NMuMg cells were also used. (Note: Current version of pcDNA3 is pcDNA3.1+/-.)
  • ID: PN62162
Catalog #s
V79020
2987f8f96837421d3dbe0684c906ea89_Citations

Mitochondrial localization of Smad5 in a human chondrogenic cell line.

Citations & References

  • Authors: Jüllig M, Stott NS
  • Journal: Biochem Biophys Res Commun (2003) 307:108-113
  • Product Usage:
  • ID: PN54243
Catalog #s
M7514
fffcc1a3964b4ad665fa2f07d7bfd086_Citations

Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment

Citations & References

  • Authors: Lohmann, F; Bieker, JJ
  • Journal: DEVELOPMENT 2008 12:2071-2082
  • Product Usage: TaqMan® Gene Expression Assays
  • ID: PN80646
Catalog #s
4331182
4351368
4351370
4351372
b24bd912005e51017d4ccaf5fede1c9a_Citations