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PRKCA (PKC alpha) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3600 | 1 mg | 5400.00 |
Description
The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
AAG6, PKCA, PRKACA, PKC-alpha
- Kinase Group
-
Ser⁄Thr Kinases: AGC Group
- Product Size
-
1 mg
- Accession Number
-
NP_002728
- Molecular Weight
-
76.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
Untagged
- Expression
-
Baculovirus
- Kinase Family
-
PKC Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
PRKCA (PKC alpha) Recombinant Human Protein View 1 Citations
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| P2227 | 20 µg | 550.00 |
Description
The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC View full product details >
General Specifications
- Gene ID
-
5578
- Species
-
Human
- Target Gene
-
protein kinase C, alpha
- Gene Aliases
-
PRKCA (PKC alpha)
- Kinase Group
-
Ser⁄Thr Kinases: AGC Group
- Product Size
-
20 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_002728
- Molecular Weight
-
76.7 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
Untagged
- Expression
-
Baculovirus
- Kinase Family
-
PKC Kinase Family
- Protein Form
-
Recombinant
Full Length
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
PRKCA (PKC alpha) Recombinant Human Protein View 2 Citations
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| P2232 | 5 µg | 308.00 |
Description
The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC View full product details >
General Specifications
- Gene ID
-
5578
- Species
-
Human
- Target Gene
-
protein kinase C, alpha
- Gene Aliases
-
PRKCA (PKC alpha)
- Kinase Group
-
Ser⁄Thr Kinases: AGC Group
- Product Size
-
5 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_002728
- Molecular Weight
-
76.7 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
Untagged
- Expression
-
Baculovirus
- Kinase Family
-
PKC Kinase Family
- Protein Form
-
Recombinant
Full Length
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
PRKCA (PKC alpha) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR1455C | 100 µg | 1250.00 |
Description
The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
PRKCA (PKC alpha)
- Kinase Group
-
Ser⁄Thr Kinases: AGC Group
- Product Size
-
100 µg
- Accession Number
-
NP_002728
- Molecular Weight
-
76.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
Untagged
- Expression
-
Baculovirus
- Kinase Family
-
PKC Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Staurosporine
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PHZ1271 | 100 µg | 176.00 |
Description
Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase.
Format/Formulation: Lyophilized
View full product details >
General Specifications
- Form
-
Lyophilized
- Gene ID
-
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
- Product Size
-
100 µg
- Purification
-
TLC
- Inhibitor Type
-
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
- Molecular Weight
-
466.5 Da
- Inhibitor Properties
-
Chemical
- Specific Inhibitor Target
-
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Culture
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-pSer (PKC) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3560 | 25 µg | 3049.00 |
Description
A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.
For use in combination with the
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3180 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence (R⁄K) View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Protein or Peptide Source
-
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
- RNAi, Epigenetics & Non-Coding RNA Research
User Ratings
LanthaScreen® Tb-pSer (PKC) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3561 | 1 mg | 17050.00 |
Description
A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.
For use in combination with the
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-PKC Substrate
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3506 | 1 mg | 655.00 |
Description
A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.
For use in combination with the LanthaScreen™ Tb-pSer (PKC Substrate) antibody (PV3560)
View full product details >
General Specifications
- Substrate
-
Fluorescein-PKC
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1919 Da
- Validated Kinases
-
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
- Amino Acid Sequence
-
Fluorescein- RFARKGSLRQKNV
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Omnia® S/T Peptide 8 Kit
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| KNZ1081 | 1 Kit | 901.00 |
Description
The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to View full product details >
General Specifications
- Form
-
Frozen
- Color
-
Green
- Readout
-
Kinetic
- Platform
-
Microplate Reader
- Technique
-
Fluorescence Intensity
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
- Label or Dye
-
Sox Chelation-Enhanced Fluorophore
- Product Size
-
1 Kit
- Target Enzyme
-
Serine/Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1237 Da
- Validated Kinases
-
MAP3K11 (MLK3), MAP3K9 (MLK1), MINK1, PRKD2 (Protein Kinase D2), PRKD1 (PKC mu), PKC
- Amino Acid Sequence
-
Ac-(Sox)PGSFRRR-NH2
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
360⁄485
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® NFAT bla HEK 293T Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1538 | 1 vial | 10250.00 |
Description
The CellSensor® NFAT-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor of Activated T Cells (NFAT) response element stably View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
CellSensor® NFAT-bla Jurkat Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1671 | 1 vial | 9949.00 |
Description
The CellSensor® NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Signaling Pathway
GPCRs
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
Go6976
| Catalog # | Unit Size | List Price | Contact Us |
|---|---|---|---|
| PHZ1094 | 500 µg |
Description
Gö6976 inhibits PKCα and PKCβ1 but has no effect on delta, epsilon, or zeta isotypes.
Format/Formulation: Lyophilized
View full product details >
General Specifications
- Form
-
Solid
- Gene ID
-
5578
- Sterility
-
Non-sterile
- Product Size
-
500 µg
- Purification
-
HPLC
- Inhibitor Type
-
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor
- Molecular Weight
-
378.4 Da
- Inhibitor Properties
-
Chemical
- Specific Inhibitor Target
-
PKCα, PKCβ1
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Culture
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
K252A
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PHZ1131 | 100 µg | 176.00 |
Description
K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive View full product details >
General Specifications
- Form
-
Lyophilized
- Gene ID
-
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
- Sterility
-
Non-sterile
- Product Size
-
100 µg
- Inhibitor Type
-
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor (Other)
- Molecular Weight
-
467.5 Da
- Inhibitor Properties
-
Chemical
- Specific Inhibitor Target
-
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Culture
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis