PRKACA (PKA) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2912 10 µg 376.00

Description

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell   View full product details >

General Specifications

Gene ID
5566
Species
Human
Target Gene
protein kinase, cAMP-dependent, catalytic, alpha
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Omnia® Bulk Substrate
Z'-LYTE™
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1-351
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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P2912
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PRKACA (PKA) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4040 1 mg 5400.00

Description

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
1 mg
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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PRKACA (PKA) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR3791B 100 µg 1250.00

Description

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
100 µg
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3560 25 µg 3049.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3560
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LanthaScreen® Tb-pCrosstide Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3564 25 µg 3458.00

Description

A general assay for serine/threonine kinases, the sequence of the Crosstide substrate is based upon GSK-3alpha/beta. The antibody is directed towards the phosphorylated Crosstide   View full product details >

General Specifications

Format
384-well plate
Gene ID
10000, 10298, 207, 208, 25400, 51347, 5566, 56164, 57144, 6197, 6198, 8536
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AKT1, AKT2, AKT3, CAMK2A, CAMK2D, PAK1, PAK4, PAK7, PRKACA, RPS6KB1, RPS6KA3, TAOK3
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3564
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PRKCA (PKC alpha) Recombinant Human Protein View 1 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2227 20 µg 550.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen™ Substrate
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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P2227
75eb6b743ada36c969853f3b0af49856_CmgtBuyProduct

Fluorescein-PKC Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3506 1 mg 655.00

Description

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.

For use in combination with the LanthaScreen™ Tb-pSer (PKC Substrate) antibody (PV3560)   View full product details >

General Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3506
792a772cf71d6e51e988229ff9567823_CmgtBuyProduct

PRKCA (PKC alpha) Recombinant Human Protein View 2 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2232 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen™ Substrate
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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P2232
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Staurosporine

Catalog # Unit Size List Price
PHZ1271 100 µg 176.00

Description

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase.

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Lyophilized
Gene ID
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
Product Size
100 µg
Purification
TLC
Inhibitor Type
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PHZ1271
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Z′-LYTE® Kinase Assay Kit - Ser/Thr 1 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3174 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon a porcine pyruvate liver kinase   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKA, AURKB, PRKACA, PRKG1, PRKG2, PRKX, RPS6KA4, RPS6KA5
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
porcine pyruvate liver kinase (LRRASLG)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3174
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Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3180 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence (R⁄K)   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research

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PV3180
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PKI [14 22] Myristoylated PTD

Catalog # Unit Size List Price
77409 1 mg 103.00

Description

cAMP-dependent protein kinase (PKA) inhibitor. This peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA).

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Lyophilized
Gene ID
5566, 5567, 5568
Sterility
Non-sterile
Product Size
1 mg
Purification
HPLC
Inhibitor Type
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
1209 Da
Inhibitor Properties
Protein
Specific Inhibitor Target
PKA
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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77409
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Omnia® S/T Peptide 6 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1061 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1617.4 Da
Validated Kinases
MAP3K10 (MLK2), PASK, RPS6KA1 (RSK1), RPS6KA2 (RSK3), RPS6KA3 (RSK2)
Amino Acid Sequence
Ac-KKRNRTLSVdP(Sox)G-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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KNZ1061
d9a86ae17838557b70dc14dc2a818246_CmgtBuyProduct

Omnia® S/T Peptide 1 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1011 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1799.6 Da
Validated Kinases
AKT1 (PKB alpha), AKT2 (PKB beta), AKT3 (PKB gamma), DAPK3, SGK (SGK1)
Amino Acid Sequence
Ac-ARKRERAYSFdP(Sox)G-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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KNZ1011
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