Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

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Catalog # Unit Size List Price
PV3180 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence (R⁄K)   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research

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PV3180
b20b314506c47c1b0d85b1a3b0ebf4d2_CmgtBuyProduct

LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3561 1 mg 17050.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3561
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PRKCB2 (PKC beta II) Recombinant Human Protein View 1 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2251 20 µg 550.00

Description

The PKC family of serine⁄threonine kinases, including PRKCB2 (PKC beta II), is activated intracellularly by signal transduction pathways. In humans, at least 12 different   View full product details >

General Specifications

Gene ID
26191, 5579
Species
Human
Target Gene
protein kinase C, beta 2
Gene Aliases
PRKCB2 (PKC beta II)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002729
Molecular Weight
77 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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P2251
dae139f8b050903efd37f752947d1928_CmgtBuyProduct

Fluorescein-PKC Substrate

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Catalog # Unit Size List Price
PV3506 1 mg 655.00

Description

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.

For use in combination with the LanthaScreen™ Tb-pSer (PKC Substrate) antibody (PV3560)   View full product details >

General Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3506
792a772cf71d6e51e988229ff9567823_CmgtBuyProduct

PRKCB1 (PKC beta I) Recombinant Human Protein View 1 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2291 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCB1 (PKC beta I), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5579
Species
Human
Target Gene
protein kinase C, beta 1
Gene Aliases
PRKCB1 (PKC beta I)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_991100.1
Molecular Weight
76.9 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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P2291
4f8c5a540dfb7cf936aa239a5379ddc3_CmgtBuyProduct

PKC-beta I & II [pT500] Rabbit Polyclonal Antibody View 1 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44955G 10 blots 299.00

Description

PKC-BETA I⁄II [pT500] PAb; Unconjugated Polyclonal antibody specific to Human PKC-β I & II [pT500]. This antibody is validated for use in Western Blot. Anti-PKC-&   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
PKC beta I&II [pT500]
Gene ID
5579
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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44955G
01409dbd99f9b058f3094206016fd670_CmgtBuyProduct

PRKCB1 (PKC beta I) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3601 1 mg 5400.00

Description

The PKC family of serine⁄threonine kinases, including PRKCB1 (PKC beta I), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
PKCB, PRKCB2, PKC-beta, PRKCB1, PKC beta I
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
1 mg
Accession Number
NP_991100.1
Molecular Weight
76.9 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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66757df8842b67be6e3a5ad8ccce512a_CmgtBuyProduct

PRKCB2 (PKC beta II) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2254 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCB2 (PKC beta II), is activated intracellularly by signal transduction pathways. In humans, at least 12 different   View full product details >

General Specifications

Gene ID
26191, 5579
Species
Human
Target Gene
protein kinase C, beta 2
Gene Aliases
PRKCB2 (PKC beta II)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002729
Molecular Weight
77 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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P2254
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PRKCB1 (PKC beta I) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2281 20 µg 550.00

Description

The PKC family of serine⁄threonine kinases, including PRKCB1 (PKC beta I), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5579
Species
Human
Target Gene
protein kinase C, beta 1
Gene Aliases
PRKCB1 (PKC beta I)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_991100.1
Molecular Weight
76.9 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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P2281
de722c84ebcaed16abaf059e57072006_CmgtBuyProduct

PKC-beta Mouse Monoclonal Antibody (clone 8/1) View 1 Citations

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Catalog # Unit Size List Price
133700 200 µg 258.00

Description

Mouse anti-PKC-BETA; Unconjugated Monoclonal antibody specific to Rat, Human PKC-β . This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-PKC-β   View full product details >

General Specifications

Reactivity
Rat
Human
Validated Application
ELISA
Immunoprecipitation
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
8⁄1
Target Gene
PKC-beta
Gene ID
25023
Label or Dye
Unconjugated
Purification
Purified
Product Size
200 µg
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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133700
2dae4a9173638a8098bc9e9425f9c58f_CmgtBuyProduct

PKC-beta II [pT641] Rabbit Polyclonal Antibody View 1 Citations

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Catalog # Unit Size List Price
44964G 10 blots 299.00

Description

PKC-BETA 11 [pT641) PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse, Rat) PKC-β II [pT641]. This antibody is validated for use in Western Blot. Anti-PKC-β   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
PKC beta II [pT641]
Gene ID
5579
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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44964G
f74cf3c8e7e04b20c0d69bfcc4ebee22_CmgtBuyProduct

Staurosporine

Catalog # Unit Size List Price
PHZ1271 100 µg 176.00

Description

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase.

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Lyophilized
Gene ID
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
Product Size
100 µg
Purification
TLC
Inhibitor Type
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PHZ1271
bd5023e5e52651226561a9d54f1c6aba_CmgtBuyProduct

LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3560 25 µg 3049.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3560
96f4f182d7a5de4d4709b2bda9f37451_CmgtBuyProduct

Omnia® S/T Peptide 8 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1081 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1237 Da
Validated Kinases
MAP3K11 (MLK3), MAP3K9 (MLK1), MINK1, PRKD2 (Protein Kinase D2), PRKD1 (PKC mu), PKC
Amino Acid Sequence
Ac-(Sox)PGSFRRR-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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KNZ1081
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