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NTRK3 (TRKC) Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4116 | 1 mg | 5400.00 |
Description
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
NTRK3 (TRKC)
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
1 mg
- Accession Number
-
NP_002521
- Molecular Weight
-
41.2 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
Neurotrophic Receptors (NTRKs)
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productNTRK3 (TRKC) Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR5998B | 100 µg | 1250.00 |
Description
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
NTRK3 (TRKC)
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
100 µg
- Accession Number
-
NP_002521
- Molecular Weight
-
41.2 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
Neurotrophic Receptors (NTRKs)
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
NTRK3 (TRKC) Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3617 | 10 µg | 376.00 |
Description
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. View full product details >
General Specifications
- Gene ID
-
4916
- Species
-
Human
- Target Gene
-
neurotrophic tyrosine kinase, receptor, type 3
- Gene Aliases
-
NTRK3 (TRKC)
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Receptor Tyrosine Kinases
- Accession Number
-
NP_002521
- Molecular Weight
-
41.2 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 510-825
- Expression
-
Baculovirus
- Kinase Family
-
Neurotrophic Receptors (NTRKs)
- Protein Form
-
Recombinant
Cytoplasmic
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Tyrosine 1 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3190 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon an optimal peptide substrate View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Tyrosine Kinase Assay
- References
-
Nature, 373, pp. 536-9 (1995)
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
BLK1, BMX, BTK, CSF1R, EPHA3, EPHA5, EPHB4, ERBB4, FES, FRK, IGF1R
ITK, KDR, MATK, NTRK1, NTRK2, NTRK3, PTK2B, PTK6, ROS1, SRMS
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Protein or Peptide Source
-
Src Substrate (EEEIYGEFE)
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-Poly GT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3610 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination with the
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Tyr (4:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3552 | 25 µg | 883.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3553 | 1 mg | 7940.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® TrkC-NFAT-bla CHO-K1 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1515 | 1 vial | 9949.00 |
Description
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell View full product details >
General Specifications
- System
-
CellSensor™
- Cell Line
-
CHO-K1
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Detection Method
-
Fluorescent
- Druggable Target
-
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
Fluorescein-Poly GAT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3611 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GAT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
NTRK3 LanthaScreen Activity Assay Validation Packet
Manual / Product Insert
NTRK3 (TRKC) Recombinant Human Protein
MSDS
NTRK3 (TRKC) Recombinant Human Protein
MSDS
Allele Variants in Functional MicroRNA Target Sites of the Neurotrophin-3 Receptor Gene (NTRK3) as Susceptibility Factors for Anxiety Disorders
Citations & References
- Authors: Muinos-Gimeno, M; Guidi, M; Kagerbauer, B; Martin-Santos, R; Navines, R; Alonso, P; Menchon, JM; Gratacos, M; Estivill, X; Espinosa-Parrilla, Y
- Journal: HUMAN MUTATION 2009 7:1062-1071
- Product Usage: Capillary Electrophoresis Systems
- ID: PN104700
Association of the neurotrophic tyrosine kinase receptor 3 (NTRK3) gene and childhood-onset mood disorders
Citations & References
- Authors: Feng, Y; Vetro, A; Kiss, E; Kapornai, K; Daroczi, G; Mayer, L; Tamas, Z; Baji, I; Kennedy, JL; Wigg, K; Kovacs, M; Barr, CL; Int Consortium Chidhood Onset Mood
- Journal: AMERICAN JOURNAL OF PSYCHIATRY 2008 5:610-616
- Product Usage: 7900HT Fast Real-Time PCR System;TaqMan® SNP Genotyping Assays
- ID: PN79819
