MAPK8 (JNK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR5340A 100 µg 1250.00

Description

MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK8 (JNK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Accession Number
NP_002741.1
Molecular Weight
47.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

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MAPK8 (JNK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3593 1 mg 5400.00

Description

MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK8 (JNK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
1 mg
Accession Number
NP_002741.1
Molecular Weight
47.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3593
51e9d0bba21ee31b38422f9ce15cf77b_CmgtBuyProduct

MAPK8 (JNK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3319 10 µg 376.00

Description

MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.   View full product details >

General Specifications

Gene ID
5599
Species
Human
Target Gene
mitogen-activated protein kinase 8
Gene Aliases
MAPK8 (JNK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002741.1
Molecular Weight
47.6 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen™ Substrate
Omnia® Bulk Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3319
373777e992854a79172f05aeef196c24_CmgtBuyProduct

MAPK8 (JNK1) Recombinant Human Protein, Inactive

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3320 100 µg 409.00

Description

MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.   View full product details >

General Specifications

Gene ID
5599
Species
Human
Target Gene
mitogen-activated protein kinase
Gene Aliases
MAPK8 (JNK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002741.1
Molecular Weight
47.6 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Inactive
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3320
3f875503123b91582eaa900b54cc0581_CmgtBuyProduct

JNK1 Mouse Monoclonal Antibody (clone 4A2G12) View 1 Citations

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Catalog # Unit Size List Price
359800 100 µg 299.00

Description

Mouse anti-JNK1; Unconjugated Monoclonal antibody specific to Human JNK1 . This antibody is validated for use in Western Blot, Immunocytochemistry/ Immunofluorescence. Anti-JNK1   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Immunofluorescence
Host
Mouse
Clonality
Monoclonal
Clone ID
4A2G12
Target Gene
JNK1
Gene ID
5599
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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359800
844d1685fc4393abf33f4b9284a016ac_CmgtBuyProduct

JNK (SAPK) [pTpY183/185] Polyclonal Antibody, Rabbit View 4 Citations

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Catalog # Unit Size List Price
44682G 10 blots 299.00

Description

This purified Rabbit anti-JNK (SAPK) [pTpY183/185] polyclonal antibody is specific to human, mouse and rat JNK1/2 [pTpY183/185]. Anti-JNK (SAPK) [pT183/pY185] polyclonal antibody   View full product details >

General Specifications

Reactivity
Rat
Mouse
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
Clonality
Polyclonal
Target Gene
JNK (SAPK) [pTpY183/185]
Gene ID
5599
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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44682G
54b866ff7175756b5013ee070b2b41aa_CmgtBuyProduct

JNK1/2 Mouse Monoclonal Antibody (clone 279Q38)

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Catalog # Unit Size List Price
AHO1362 100 µg 299.00

Description

JNK1/2 MAb hu, ms, rt; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat JNK1/2. This antibody is validated for use in Western Blot. Anti-JNK1/2 recognizes the   View full product details >

General Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
279Q38
Target Gene
JNK1/2
Gene ID
116554, 26419, 5599
Label or Dye
Unconjugated
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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AHO1362
10351c0c82b0e74f32dac53a74edd991_CmgtBuyProduct

LanthaScreen® Tb-pATF2 (pSer71) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4452 1 mg 17050.00

Description

A member of the leucine zipper family of DNA binding proteins, ATF2 (activating transcription factor 2) is phosphorylated at Thr71 by members of the JNK and p38 families of kinases   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV4452
ac5196f23f7a8f8937d6c3893d27ad37_CmgtBuyProduct

GFP-ATF2 (19-96)

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Catalog # Unit Size List Price
PV4445 20 nmol 661.00

Description

A truncated version (residues 19-96) of ATF2 has been expressed as a fusion with GFP (Green Fluorescent Protein) to act as a substrate for the JNK and p38 families of kinases.
  View full product details >

General Specifications

Substrate
ATF2 (19-96)
Label or Dye
GFP (EmGFP)
Product Size
20 nmol
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
478000 Da
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV4445
e2032308d30e1ed8fd1feed91ee976dc_CmgtBuyProduct

CellSensor® AP-1-bla HEK293T Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1658 1 vial 9949.00

Description

The CellSensor® AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells. The cell   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development

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K1658
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JNK1 Rabbit Polyclonal Antibody View 2 Citations

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Catalog # Unit Size List Price
44690G 100 µl 299.00

Description

JNK1 PAN PAb hu, ms, rt ; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat JNK1. This antibody is validated for use in Western Blot. Anti-JNK1 recognizes the   View full product details >

General Specifications

Reactivity
Rat
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
JNK1
Gene ID
5599
Label or Dye
Unconjugated
Purification
Purified
Product Size
100 µl
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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44690G
1ec2d59f517adcfc75b8f9d1677b7d1b_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 4 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3177 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon glycogen synthase, containing   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
Biochem J. vol 296, pp. 843-9 (1993), J. Biol Chem, vol. 260, pp 14471-6 (1985)
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPKAPK2, MAPKAPK3, MAPKAPK5, STK22B, STK22D
CAMK2A, CAMK2D, MAPK8, MAPK9, MAPK10, MAPK14
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
based on Ser 7 glycogen synthase (KKLNRTLSVA)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3177
6ddf686d8f5578214eed12c5385808db_CmgtBuyProduct

LanthaScreen® Tb-p-c-jun (pSer73) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4453 25 µg 3049.00

Description

A part of the Activating protein-1 (AP-1) transciption factor, c-Jun is phosphorylated at Ser73 by members of the JNK family.

For use in combination with the GFP-c-Jun   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK8, MAPK9, MAPK10, NLK
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4453
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JNK1/2 [pT183/pY185] Monoclonal Antibody (clone D12H7L17), ABfinity™ Recombinant View 2 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
700031 100 µg 299.00

Description

This purified ABfinityâ„¢ recombinant rabbit anti-JNK1/2 [pT183/pY185] monoclonal antibody is specific to Human JNK1/2 [pT183/pY185] and does not recognize non-phosphorylated   View full product details >

General Specifications

Reactivity
Human
Validated Application
Immunohistochemistry
Flow Cytometry
Immunofluorescence
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D12H7L17
Antibody Fragment
Whole Antibody
Target Gene
JNK1/2 [pT183/pY185]
Gene ID
5599, 5601
Accession Number
P45983, P45984
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Confocal Microscope
Fluorescence Microscope
Flow Cytometer
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Quantity
1
Volume
200 µl
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis

User Ratings

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700031
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