MAPK3 (ERK1) Recombinant Human Protein, Inactive

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3312 100 µg 409.00

Description

MAPK3 (ERK1) is a serine⁄threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Gene ID
5595
Species
Human
Target Gene
mitogen-activated protein kinase 3
Gene Aliases
MAPK3 (ERK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002737
Molecular Weight
70.8 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Full Length
Recombinant
Inactive
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3312
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MAPK3 (ERK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3594 1 mg 9450.00

Description

MAPK3 (ERK1) is a serine⁄threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK3 (ERK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
1 mg
Accession Number
NP_002737
Molecular Weight
70.8 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

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PV3594
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MAPK3 (ERK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR5254B 100 µg 1995.00

Description

MAPK3 (ERK1) is a serine⁄threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK3 (ERK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Accession Number
NP_002737
Molecular Weight
70.8 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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MAPK3 (ERK1) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3311 10 µg 376.00

Description

MAPK3 (ERK1) is a serine⁄threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.   View full product details >

General Specifications

Gene ID
5595
Species
Human
Target Gene
mitogen-activated protein kinase 3
Gene Aliases
MAPK3 (ERK1)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002737
Molecular Weight
70.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinases
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3311
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ERK1/2 (MAP kinase) Monoclonal Antibody, Mouse (ERK-7D8) View 5 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
136200 200 µg 279.00

Description

Mouse anti-MAP Kinase (ERK1+ERK2) Monoclonal Antibody is specific to Canine, Human, Mouse, Rat, and recombinant ERK1+2. This unconjugated Mouse anti-MAP Kinase monoclonal antibody   View full product details >

General Specifications

Reactivity
Canine
Rat
Mouse
Human
Validated Application
Immunohistochemistry
Immunoprecipitation
Electrophoretic Mobility Shift Assay
ELISA
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
ERK-7D8
Target Gene
ERK1/2 (MAP kinase)
Gene ID
116590
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
200 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research

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136200
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ERK1/2 Rabbit Polyclonal Antibody View 2 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
617400 100 µg 268.00

Description

Rabbit anti-MAP Kinase (ERK1+ERK2); Unconjugated Polyclonal antibody specific to Human, Mouse, Rat ERK1+2. This antibody is validated for use in Western Blot, Immunohistochemistry,   View full product details >

General Specifications

Reactivity
Rat
Mouse
Human
Validated Application
ELISA
Immunohistochemistry
Immunoprecipitation
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
ERK1/2
Gene ID
116590, 26413, 26417, 50689, 5594, 5595
Label or Dye
Unconjugated
Purification
Epitope Affinity Purified
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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617400
d51fc607358e4a348fb01c583c431c79_CmgtBuyProduct

ERK 1/2 (Total) Singleplex Bead Kit View 1 Citations

See all Singleplex Assays

Catalog # Unit Size List Price
LHO0231 100 tests 299.00

Description

This Singleplex bead kit comprises the analyte specific components for the measurement of total ERK1⁄2 (Extracellular signal-Regulated protein Kinase) in cell lysates or   View full product details >

General Specifications

Marker
ERK1⁄2 (total)
System
Luminex®
Gene ID
5595
Species
Human
Platform
Luminex®
Bead Type
Polystyrene
Bead Region
57
Gene Symbol
MAPK3
Sensitivity
0.05 ng/ml
Target Gene
mitogen-activated protein kinase 3
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, MGC20180, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
R-PE
Product Size
100 tests
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002737.2
NP_001035145.1
NM_001109891.1
NM_001040056.1
NM_002746.2
NP_001103361.1
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development

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LHO0231
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Omnia® S/T Peptide 17 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1171 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Gene ID
5594, 5595, 6300
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1075.8 Da
Validated Kinases
MAPK01 (ERK2), MAPK03 (ERK1)
Amino Acid Sequence
Ac-(Sox)PLSPGPF-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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KNZ1171
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IBMX

Catalog # Unit Size List Price
PHZ1124 1 g 320.00

Description

IBMX is a nonspecific inhibitor of phosphodiesterases that also possesses adenosine agonist activity.

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Solid
Gene ID
5595
Sterility
Non-sterile
Product Size
1 g
Purification
TLC
Inhibitor Type
Phosphodiesterase Inhibitor
Molecular Weight
222.2 Da
Research Category
Signal Transduction
Inhibitor Properties
Chemical
Specific Inhibitor Target
Phosphodiesterases (also has adenosine agonist activity)
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Cell Culture
  • Proteins, Expression, Isolation & Analysis

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PHZ1124
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GFP-ATF2 (19-96)

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV4445 20 nmol 661.00

Description

A truncated version (residues 19-96) of ATF2 has been expressed as a fusion with GFP (Green Fluorescent Protein) to act as a substrate for the JNK and p38 families of kinases.
  View full product details >

General Specifications

Substrate
ATF2 (19-96)
Label or Dye
GFP (EmGFP)
Product Size
20 nmol
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
478000 Da
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4445
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LanthaScreen® Tb-pATF2 (pSer71) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4452 1 mg 17050.00

Description

A member of the leucine zipper family of DNA binding proteins, ATF2 (activating transcription factor 2) is phosphorylated at Thr71 by members of the JNK and p38 families of kinases   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Terbium (Tb)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV4452
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ERK1/2 [pTpY185/187] Polyclonal Antibody, Rabbit View 2 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44680G 10 blots 299.00

Description

This purified Rabbit Anti-ERK 1/2 [pTpY185/187] Polyclonal Antibody is specific to human, mouse, and rat ERK 1/2 [pT185/pY187]. Anti-ERK1/2 [pT185/pY187] antibody recognizes the   View full product details >

General Specifications

Reactivity
C. elegans
Drosophila
Chicken
Bovine
Mouse
Human
Rat
Xenopus
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
Clonality
Polyclonal
Target Gene
ERK1/2 [pTpY185/187]
Gene ID
5595
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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44680G
79a10412807dc5fd8bdc1cdfa49f0591_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 3 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3176 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine MBP Thr-97 derived   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAPK1, MAPK3, MAPK12, MAPK13, MAP2K1, MAP2K2, MAP3K6, MAP2K8
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
Bovine MBP, Thr-97 derived peptide S5
Consensus seq Pro-X-(Ser⁄Thr)-Pro (APRTPGGRR)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

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PV3176
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ERK1/2 (pan) Polyclonal Antibody, Rabbit View 4 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44654G 100 µl 299.00

Description

This purified rabbit anti-ERK1/2 polyclonal antibody is specific to human, mouse, rat and bovine ERK 1+2. Anti-ERK1+2 polyclonal antibody recognizes the expressed product of the   View full product details >

General Specifications

Reactivity
Bovine
Rat
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
ERK1/2 (pan)
Gene ID
5595
Label or Dye
Unconjugated
Product Size
100 µl
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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44654G
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