MAPK10 (JNK3) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4563 10 µg 376.00

Description

MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4.   View full product details >

General Specifications

Mass
10 µg
Species
Human
Target Gene
mitogen-activated protein kinase 10
Gene Aliases
MAPK10 (JNK3)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002744
Molecular Weight
76.6 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen™ Antibody
LanthaScreen™ Substrate
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Tag Position
N-Terminal
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4563
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MAPK10 (JNK3) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR6983B 100 µg 1250.00

Description

MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK10 (JNK3)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
100 µg
Accession Number
NP_002744
Molecular Weight
76.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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MAPK10 (JNK3) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4564 1 mg 5400.00

Description

MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAPK10 (JNK3)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Product Size
1 mg
Accession Number
NP_002744
Molecular Weight
76.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
MAP Kinases
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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LanthaScreen® Tb-pATF2 (pSer71) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4452 1 mg 17050.00

Description

A member of the leucine zipper family of DNA binding proteins, ATF2 (activating transcription factor 2) is phosphorylated at Thr71 by members of the JNK and p38 families of kinases   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4452
ac5196f23f7a8f8937d6c3893d27ad37_CmgtBuyProduct

GFP-ATF2 (19-96)

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV4445 20 nmol 661.00

Description

A truncated version (residues 19-96) of ATF2 has been expressed as a fusion with GFP (Green Fluorescent Protein) to act as a substrate for the JNK and p38 families of kinases.
  View full product details >

General Specifications

Substrate
ATF2 (19-96)
Label or Dye
GFP (EmGFP)
Product Size
20 nmol
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
478000 Da
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4445
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LanthaScreen® Tb-p-c-jun (pSer73) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4453 25 µg 3049.00

Description

A part of the Activating protein-1 (AP-1) transciption factor, c-Jun is phosphorylated at Ser73 by members of the JNK family.

For use in combination with the GFP-c-Jun   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK8, MAPK9, MAPK10, NLK
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4453
c7cff9952bc3a9722e13d5ceda6a472e_CmgtBuyProduct

LanthaScreen® Tb-pATF2 (pSer71) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4451 25 µg 3049.00

Description

A member of the leucine zipper family of DNA binding proteins, ATF2 (activating transcription factor 2) is phosphorylated at Ser71 by members of the JNK and p38 families of kinases   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK1, MAPK3, MAPK8, MAPK9, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4451
e3385ad5fb0025d6cff1c4adb927b0f6_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 4 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3177 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon glycogen synthase, containing   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
Biochem J. vol 296, pp. 843-9 (1993), J. Biol Chem, vol. 260, pp 14471-6 (1985)
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPKAPK2, MAPKAPK3, MAPKAPK5, STK22B, STK22D
CAMK2A, CAMK2D, MAPK8, MAPK9, MAPK10, MAPK14
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
based on Ser 7 glycogen synthase (KKLNRTLSVA)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3177
6ddf686d8f5578214eed12c5385808db_CmgtBuyProduct

LanthaScreen® Tb-p-c-jun (pSer73) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4454 1 mg 17050.00

Description

A part of the Activating protein-1 (AP-1) transciption factor, c-Jun is phosphorylated at Ser73 by members of the JNK family.

For use in combination with the GFP-c-Jun   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Terbium (Tb)
GFP (EmGFP)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
MAPK8, MAPK9, MAPK10, NLK
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4454
4c39060155c478054bad156cd1289432_CmgtBuyProduct

GFP-C-Jun (1-179)

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV4446 20 nmol 661.00

Description

A truncated version (residues 1-179) of c-Jun has been expressed as a fusion with GFP (Green Fluorescent Protein) to act as a substrate for the JNK family of kinases.

For   View full product details >

General Specifications

Substrate
c-Jun (1-179)
Label or Dye
GFP (EmGFP)
Product Size
20 nmol
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
51.6 kDa
Validated Kinases
MAPK8, MAPK9, MAPK10, NLK
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4446
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Omnia® S/T Peptide 10 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1101 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Gene ID
5599
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1869.6 Da
Validated Kinases
MAPK08 (JNK1), MAPK10 (JNK3)
Amino Acid Sequence
Ac-(Sox)PGTPSGEAPNQALLR-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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KNZ1101
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MAPK10 LanthaScreen Binding Assay Validation Packet

Manual / Product Insert

Catalog #s
PV4563
c26eb42ae1a8b1ea54f325f051d6753f_Manuals

MAPK10 LanthaScreen Activity Assay Validation Packet

Manual / Product Insert

Catalog #s
PV4563
0e364cf4a1a53aa0afe4627cbc86d145_Manuals

MAPK10 (JNK3) Recombinant Human Protein

MSDS

MSDS Files
PV4563
Catalog #s
PV4563
27fde05994bcdc40e9fc57b6e9de08b6_MSDS