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Cell Signaling Pathways

Empower your research today using Invitrogens comprehensive portfolio of products and services to investigate cell signaling pathways and signal transduction.
JAK1 [pY1022/23] Monoclonal Antibody (clone 59H4L5), ABfinity™ Recombinant
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 700028 | 100 µg | 299.00 |
Description
This purified ABfinity™ recombinant rabbit anti-JAK1 [pY1022/23] monoclonal antibody is specific to JAK1 [pY1022/23] and does not recognize non-phosphorylated JAK1. Based on View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- SubClass (Isotype)
-
IgG
- Clonality
-
Monoclonal
- Clone ID
-
59H4L5
- Antibody Fragment
-
Whole Antibody
- Target Gene
-
JAK1 [pY1022/pY1023]
- Gene ID
-
3716
- Accession Number
-
P23458
- Label or Dye
-
Unconjugated
- Target Modification State
-
Phospho
- Purification
-
Affinity Purified
- Concentration
-
0.5 mg⁄ml
- Form
-
Liquid
- Neutralizing Antibody
-
No
- Product Size
-
100 µg
- Quantity
-
1
- Volume
-
200 µl
- Research Category
-
Signal Transduction
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK1 [pYpY1022/1023] Polyclonal Monoclonal Antibody, Rabbit View 3 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 44422G | 10 blots | 299.00 |
Description
This rabbit anti-JAK1 [pYpY1022/1023] polyclonal antibody is specific to human and mouse JAK1 [pYpY1022/1023] protein. Janus Kinase 1 (JAK1) is a 130 kDa tyrosine kinase involved View full product details >
General Specifications
- Reactivity
-
Mouse
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- Clonality
-
Polyclonal
- Target Gene
-
JAK1 [pYpY1022/1023]
- Gene ID
-
3716
- Label or Dye
-
Unconjugated
- Target Modification State
-
Phospho
- Product Size
-
10 blots
- Research Category
-
Signal Transduction
- Purity or Quality Grade
-
Azide Free
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK1 Pan Rabbit Polyclonal Antibody View 3 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 44400G | 10 blots | 179.00 |
Description
JAK1 PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat JAK1. This antibody is validated for use in Western Blot. Anti-JAK1 recognizes the expressed product of the View full product details >
General Specifications
- Reactivity
-
Rat
Mouse
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- Clonality
-
Polyclonal
- Target Gene
-
JAK1 Pan
- Gene ID
-
3716
- Label or Dye
-
Unconjugated
- Product Size
-
10 blots
- Research Category
-
Signal Transduction
- Purity or Quality Grade
-
Azide Free
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK1 Recombinant Human Protein
See all Cytoplasmic Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4775 | 1 mg | 8800.00 |
Description
Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
JAK1, JAK1A, JAK1B
- Product Size
-
1 mg
- Protein Form
-
Catalytic
- Accession Number
-
NP_002218.2
- Molecular Weight
-
60.8 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
JAK Kinase Family
- Kinase Group
-
Tyrosine Kinases
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK1 Recombinant Human Protein
See all Cytoplasmic Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR8767C | 100 µg | 1385.00 |
Description
Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
JAK1, JAK1A, JAK1B
- Product Size
-
100 µg
- Protein Form
-
Catalytic
- Accession Number
-
NP_002218.2
- Molecular Weight
-
60.8 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
JAK Kinase Family
- Kinase Group
-
Tyrosine Kinases
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK1 Recombinant Human Protein
See all Cytoplasmic Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4774 | 10 µg | 376.00 |
Description
Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways. View full product details >
General Specifications
- Gene ID
-
3716
- Species
-
Human
- Target Gene
-
Janus kinase 1
- Gene Aliases
-
JAK1, JAK1A, JAK1B
- Product Size
-
10 µg
- Protein Form
-
Recombinant
Cytoplasmic
Catalytic
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Cytoplasmic Tyrosine Kinases
- Accession Number
-
NP_002218.2
- Molecular Weight
-
60.7 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 866-1154
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
JAK Kinase Family
- Kinase Group
-
Tyrosine Kinases
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
JAK/STAT Rabbit Polyclonal Antibody
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 44429G | 7 vials | 412.00 |
Description
JAK⁄STAT Sampler Pack (7 vials) PAb hu, ms, rt, sw, mk (Invitrogen); Unconjugated Polyclonal antibody specific to Multiple JAK⁄STAT Sampler Pack. This antibody is View full product details >
General Specifications
- Reactivity
-
Rat
Mouse
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- Clonality
-
Polyclonal
- Clone ID
-
Sampler Pack
- Target Gene
-
JAK/STAT
- Label or Dye
-
Unconjugated
- Target Modification State
-
Phospho
- Product Size
-
7 vials
- Research Category
-
Signal Transduction
- Purity or Quality Grade
-
Azide Free
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-pSTAT3 [pTyr705] Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4847 | 1 mg | 16840.00 |
Description
A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
GFP (EmGFP)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
JAK1, JAK2, JAK3, TYK2
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® ISRE-bla HEK293T Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1655 | 1 vial | 9949.00 |
Description
Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor® ISRE-bla HEK 293T cell line is responsive to interferon alpha View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
CellSensor® ISRE-bla RA-1 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1674 | 1 vial | 9949.00 |
Description
The CellSensor® ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE). This cell line was View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
CellSensor® SIE-bla THP-1 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1652 | 1 vial | 9949.00 |
Description
The CellSensor® SIE-bla THP-1 cell line contains a beta-lactamase reporter gene under control of the Sis Inducible Element (SIE), stably integrated into THP-1 cells. To View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
CellSensor® SIE-bla ME-180 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1648 | 1 vial | 9949.00 |
Description
The CellSensor® SIE-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Sis-Inducible Element (SIE) stably integrated into ME-180 cells. To View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
CellSensor® SIE-bla HEK293T Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1649 | 1 vial | 9949.00 |
Description
The CellSensor® SIE-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the SIE response element stably integrated into HEK 293T cells. The cell View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development